血清降钙素原预测胆道梗阻患者的胆道感染  

Serum procalcitonin measurement for detection of biliary infection in patients with biliary tract obstruction

作　　者：段键[1] 李智涛[1] 曾仲[1] 邹文香[1] 黄智[1] 彭沙沙[1] 

机构地区：[1]昆明医科大学第一附属医院器官移植中心,云南省昆明市650032

出　　处：《世界华人消化杂志》2014年第12期1739-1742,共4页World Chinese Journal of Digestology

基　　金：云南省教育厅科学研究基金资助项目;No.2013C245~~

摘　　要：目的:探讨通过检测血清降钙素原(procalcitonin,PCT)评估胆道梗阻患者是否存在隐匿性胆道感染的价值.方法:胆道梗阻而无胆管炎临床发作的45例患者患者术前抽取血清检测降钙素原、C反应蛋白(C-reactive protein,CRP)、白细胞(white blood cell,WBC)计数,术中留取胆汁培养;按照胆汁培养结果分为胆道感染组和非感染组,两组间统计分析降钙素原有无差异.结果:本研究45例患者,其中感染组(14例),对照组(31例),在感染组PCT检测值为7.15ng/L±10.06 ng/L,较对照组(0.29 ng/L±0.38ng/L)明显升高,两组均值差异有统计学意义(P<0.05).结论:降钙素原可作为胆道隐性感染的敏感、准确、及时预测指标.AIM： To prospectively evaluate procalcitonin （PCT） as a marker for the detection of biliary tract infection in patients with biliary tract obstruction. METHODS： Forty-five patients were divided into two groups based on results of bile cultivation. Blood samples were collected for measuring PCT, CRP, and WBC when patients were admitted. RESULTS： Of the 45 patients, 14 had biliary tract infection and 31 did not have. PCT level was significantly higher in the culture positive group （7.15 ng/L ± 10.06 ng/L） as compared to the culture negative group （0.29 ng/L ± 0.38 ng/L） （P 〈 0.05）, while there were no statisticalsignificances in CRP and WBC between the two groups. CONCLUSION： This study showed that PCT could be used as a marker to detect biliary tract infection promptly.

关 键 词：降钙素原 胆道疾病 感染 

分 类 号：R657.43[医药卫生—外科学]