沧州地区565例变应性鼻炎患者血清sIgE结果分析  

Analysis on the results of serum specific IgE determination among 565 cases with allergic rhinitis in Cangzhou district

作　　者：王丽[1] 王寅[1] 王小奇[1] 林文森[2] 王泽海[1] 

机构地区：[1]河北省青县人民医院耳鼻咽喉头颈外科,062650 [2]天津市南开医院耳鼻咽喉头颈外科

出　　处：《中国中西医结合耳鼻咽喉科杂志》2014年第2期109-111,135,共4页Chinese Journal of Otorhinolaryngology in Integrative Medicine

摘　　要：目的：调查沧州地区变应性鼻炎患者的变应原谱分布情况。方法对2011年5月～2013年4月间在本院就诊疑为变应性鼻炎的患者进行血清sIgE检测，统计分析其阳性变应原分布情况。结果565例患者中，307例（54.3%）血清sIgE检测呈阳性。其中吸入组变应原阳性率90.2%（277/307），显著高于食入组变应原阳性率30.6%（P＜0.01）。前6位阳性变应原依次为户尘螨（29.9%），矮豚草、蒿、葎草、藜（16.1%），屋尘螨（14.5%），点青霉、分枝孢霉、烟曲霉、交链孢霉（11.7%），柏、榆、柳、栎、桦、枫、胡桃、梧桐、杨（7.4%），腰果（7.1%），其它变应原阳性率均在6%以下。狗毛皮屑（2.1%）和猫毛皮屑（1.8%）在吸入组中阳性率最低。结论户尘螨、屋尘螨和矮豚草、蒿等是沧州地区变应性鼻炎患病的主要变应原。Objective To investigate the distributing status of sensitive allergen spectrum for patients with allergic rhinitis （AR） in Cangzhou district.Methods Serum specific IgE （sIgE）, as the indicator of sensitive allergen spectrum distribution, was detected among 565 patients with clinically suspected AR in our Hospital from May, 2011 to Apr, 2013. SPSS13.0 software was used to analyze these data for sensitive allergen distribution.Results Among these 565 cases investigated, 307 were determined with positive serum sIgE （54.3%）, with the positive rate （90.2%, 277/307） of sensitive allergens in inhalation group significantly higher than that （30.6%,P〈0.01） in food group. The first 6 kinds of sensitive allergen with higher positive rate were household dust mites （29.9%）, short ragweed, artemisia, humulus and grass quinoa （16.1%）, house dust mites （14.5%）; penicillium notatum, branch mould spore, smoke aspergillus and cross-linking mould spore （11.7%）, cypress, elm, willow, oak, birch, maple, walnut, phoenix tree and poplar （7.4%）, and cashew nuts （7.1%）, while the positive rate of other sensitive allergens were all below 6%. Sensitive allergens with the lowest positive rates were dog dander （2.1%） and cat hair dander （1.8%） in inhalation allergens.Conclusions The most commonly seen sensitive allergens were household dust mites, house dust mites, short ragweed and Artemisia responsible for AR in Cangzhou district.

关 键 词：变应性鼻炎 变应原 血清sIgE 分布特征 

分 类 号：R765.21[医药卫生—耳鼻咽喉科]