高血压患者心房颤动危险因素分析  

Risk factors for atrial fibrillation in hypertensive patients

作　　者：齐静[1] 姜钧文[1] 陈韦[1] 王艳春[1] 李蒙[1] 于乐[1] 周鑫[1] 侯平[1] 

机构地区：[1]辽宁中医药大学附属医院心内科,辽宁沈阳110032

出　　处：《中华实用诊断与治疗杂志》2014年第6期566-567,共2页Journal of Chinese Practical Diagnosis and Therapy

基　　金：辽宁省科技厅科研基金(2012225018)

摘　　要：目的探讨高血压患者引起心房颤动（房颤）的危险因素。方法194例高血压患者分为阵发性房颤组52例、永久性房颤组60例和非房颤组82例（对照组）；记录3组性别、年龄、家族史、目前用药情况、超声心动图以及血尿酸、C反应蛋白水平等，采用logistic回归分析房颤发生危险因素。结果3组年龄、β受体阻滞剂应用、左心房内径、左室射血分数及血尿酸、C反应蛋白水平比较差异有统计学意义（P〈0．05）；单因素logistic回归分析结果显示，性别、年龄、左心房内径、B受体阻滞剂的应用与房颤相关（P〈0．05）；logistic回归分析结果显示，永久性房颤与血尿酸独立相关（OR=3．096，95％CI：1.249～7．677，P=0．015），阵发性房颤与血尿酸无明显相关性（OR=0．932，95％CI：0．355～2．444，P=0．886）。结论血尿酸水平增高可能是永久性房颤发生的危险因素。Objective To explore the risk factors for atrial fibrillation （AF） in hypertensive patients. Methods A total of 194 hypertensive patients were divided into paroxysmal AF group （n= 52）, permanent AF group （n= 60） and non-AF group （n=82）. The gender, age, family history, current medications, echocardiography findings, serum uric acid （SUA） and C-reactive protein levels were recorded in three groups. Logistic regression was used to analyze the risk factors for AF. Results There were significant differences in the age, β-blocker, left atrial diameter （LAD）, left ventricular ejection fraction （LVEF）, SUA and C-reactive protein among three groups （P〈0.05）. Univariate logistic analysis showed that the gender, age, LAD and l？-blocker were correlated with AF （P〈0. 05）. Logistic regression analysis showed permanent AF was independently correlated with SUA （OR= 3. 096, 95% CI： 1. 249 to 7. 677, P= 0.015）, and paroxysmal AF was not correlated with SUA （OR=0. 932, 95%CI：0. 355 to 2. 444, P=0. 886）. Conclusions Increased SUA level is a risk factor for permanent AF.

关 键 词：心房颤动 高血压 血尿酸 

分 类 号：R544.1[医药卫生—心血管疾病]