营养代谢组学及其在奶牛营养研究中的应用  

Nutritional Metabolomics and Its Application in Dairy Cow Nutrition

作　　者：孙会增 刘建新[1] 

机构地区：[1]浙江大学奶业科学研究所,浙江杭州310058

出　　处：《中国畜牧杂志》2014年第11期81-85,共5页Chinese Journal of Animal Science

基　　金：国家奶牛产业技术体系(CARS-37)

摘　　要：代谢组学作为一种新兴的技术与分析手段,通过研究生物体体液或组织代谢物的变化来认识其生理与生化状态,进而解释隐藏其后的生物学规律。营养代谢组学是后基因组时代营养科学与代谢组学交叉形成的一门新的分支学科,着力从分子水平研究膳食营养与代谢产物的交互作用及其对机体健康的影响,代表了营养学学科发展的前沿。本文从代谢组学的概念、代谢组学研究流程、营养代谢组学及其在奶牛营养研究中的应用进行了综述。目前营养代谢组学在奶牛营养研究中的应用主要集中在瘤胃、乳腺、血液等几个器官,通过对差异物质的鉴定、关键代谢通路的解析在分子水平上研究营养代谢机制。As an emerging technology and analytic approach,metabolomics has been used to understand the body＇s physiological and biochemical status by studying metabolites in fluids or tissues,and then further interpretation of the biological principles.Nutritional metabolomics is a new subdiscipline formed by intersection of nutrition science and metabolomics in the post-genomic era.It focuses on the interaction between diet nutrition,metabolism and effects on the body＇s health at the molecular level.This article provides a brief introduction to metabolomics,the metabolomics research process,nutritional metabonomics and its application in dairy cow nutrition.The nutritional metabolomics applications on dairy cow main focused on rumen,breast and blood.Studying the mechanism of nutritional metabolism at the molecular level by identification significant different metabolites and key metabolic pathways.

关 键 词：代谢组学 营养代谢组学 奶牛 

分 类 号：S823.5[农业科学—畜牧学]