无锡市2005-2010年儿童流感相关超额住院估计  

Influenza-associated-excess-hospitalization in children,Wuxi city,Jiangsu province,2005-2010

作　　者：冯录召[1] 费方荣[2] 李飒[1] 钱燕华[3] 祖荣强[4] 余宏杰[1] 

机构地区：[1]中国疾病预防控制中心传染病预防控制处传染病监测预警重点实验室,北京102206 [2]浙江省疾病预防控制中心 [3]江苏省无锡市疾病预防控制中心 [4]江苏省疾病预防控制中心

出　　处：《中华流行病学杂志》2014年第6期699-703,共5页Chinese Journal of Epidemiology

基　　金：中美新发和再发传染病合作项目（5U2GGH000018-02）；无锡市卫生局重大项目（G201201）

摘　　要：目的：估计2005-2010年无锡市0～14岁儿童流感相关超额住院率。方法收集无锡市14家二级及以上医院流感及肺炎、呼吸系统疾病住院资料及我国南方病毒学监测数据，拟合负二项回归模型，估计流感相关超额住院情况。结果2005-2010年无锡市0～14岁儿童住院率平均为91.6‰（79.2‰～99.3‰），其中，呼吸系统疾病住院占总住院人数的54.2%，流感及肺炎住院占38.1%。年均流感及肺炎超额住院率为1.28‰（95%CI：0.29‰～4.84‰），呼吸系统疾病超额住院率为2.18‰（95%CI：0.61‰～6.79‰）。甲型H1N1流感在2009年导致993例流感及肺炎超额住院和1042例呼吸系统疾病超额住院，对应的超额住院率分别为1.14‰和1.20‰。结论无锡市季节性流感和甲型H1N1流感大流行对0～14岁儿童产生相当的超额住院。Objective To estimate the rates due to influenza-associated-excess-hospitalization in children aged 0-14 years in Wuxi city,Jiangsu province in 2005-2010. Methods We collected data on hospitalization due to influenza,pneumonia and other respiratory diseases from fourteen 2nd level or above hospitals in Wuxi,as well as data on influenza virological surveillance in southern China to fit the negative binomial regression models,to estimate the rate on influenza-associated-excess hospitalization. Results During 2005-2010,an average annual hospitalization rate appeared as 91.6‰（79.2‰-99.3‰）. Among the total hospitalization eases,respiratory diseases accounted for 54.2%,while both influenza and pneumonia accounted for 38.1%. The average annual influenza-associated-excess-hospitalization rates due to influenza and pneumonia appeared as 1.28‰（95%CI：0.29‰-4.84‰）,while 2.18‰（95%CI：0.61‰-6.79‰） due to respiratory diseases. In 2009,A（H1N1）pdm induced influenza pandemic caused 993 excess hospitalizations due to influenza/pneumonia and 1 042 excess hospitalizations due to respiratory diseases,with rates as 1.14‰ and 1.20‰ respectively. Conclusion Both seasonal and pandemic A（H1N1）pdm influenza caused considerable burden on hospitalization in children aged 0-14 years in Wuxi.

关 键 词：季节性流感 甲型H1N1流感 超额住院 负二项回归 儿童 

分 类 号：R725.1[医药卫生—儿科]