宁夏地区2011年病毒性腹泻病例病原学研究  

Etiological study on cases with viral diarrhea in Ningxia during 2011

作　　者：詹军[1] 马江涛[1] 陈慧[1] 袁芳[1] 马学旻[1] 刘翔[1] 郝琼[1] 

机构地区：[1]宁夏回族自治区疾病预防控制中心,银川750004

出　　处：《中华流行病学杂志》2014年第6期729-732,共4页Chinese Journal of Epidemiology

基　　金：宁夏自然科学基金项目（NZ13219）;宁夏卫生厅重点科研计划课题（2012040）

摘　　要：目的：了解2011年宁夏地区腹泻病例中轮状病毒（HRV）、杯状病毒（HuCV）、星状病毒（HAstV）及肠道腺病毒（HAdV）感染情况。方法2011年收集宁夏不同地区腹泻病例的粪便标本，采用ELISA法检测A组HRV，阳性标本采用RT-PCR法进行分型鉴定；采用RT-PCR或PCR法检测HuCV、HAstV和HAdV。结果共收集腹泻病例粪便标本690份，其中HRV占2.17%（15/690）、HuCV占21.74%（150/690）、HAstV占3.19%（22/690）、HAdv占6.52%（45/690）、混合感染占4.20%（29/690）。15份HRV G血清型与P基因型以G1、G3、P[4]型为优势株。结论2011年宁夏地区病毒性腹泻主要以＜2岁婴幼儿为主，HuCV是主要病原体。Objective To investigate the etiological characteristics of human rotavirus （HRV）,human calicivirus （HuCV）,human astrovirus （HAstV） and human enteral adenovirus （HAdV）in Ningxia province during 2011. Methods Stool specimen was collected from acute diarrhea case of Ningxia during 2011. HRV was detected by ELISA and serotype/genotype identified on those RT-PCR positive specimens. HuCV,HAstV and HAdV were detected by RT-PCR. Results In this study,a total of 690 specimens were detected,with the infection rates of HRV,HuCV,HAstV and HAdV as 2.17%,21.74%,3.19%and 6.52%,respectively. Co-infections were found in 4.20%of all the samples being tested. Among 15 HRV positive cases,serotypes G1,G3 and P[4]were the most predominant strains. Conclusion Children who were under 2 years of age were the majority among patients infected by diarrhea viruses while HuCV was recognized as the main pathogen responsible for the viral diarrhea casses in Ningxia,2011.

关 键 词：病毒性腹泻 轮状病毒 杯状病毒 星状病毒 肠道腺病毒 

分 类 号：R725.1[医药卫生—儿科]