乳房链球菌对克林霉素耐药基因的定位  

Location of the Resistant Gene to Clindamycin in Streptococcus uberis

作　　者：冯现维[1] 韩文瑜[1] 雷连成[1] 江文正[1] 王世若[1] 

机构地区：[1]解放军军需大学动物科技系,长春130062

出　　处：《中国预防兽医学报》2001年第2期134-136,共3页Chinese Journal of Preventive Veterinary Medicine

摘　　要：采用试管稀释法和纸片法测定 9株乳房链球菌对克林霉素的耐药性 ,通过PCR反应检测克林霉素的耐药性基因 ,并进行测序比较。发现克林霉素对乳房链球菌的抗菌活力较强 ,克林霉素耐药基因同时存在于乳房链球菌的染色体和质粒上。A total 9 isolates of the Streptococcus uberis were tested for minimal inhibitory concentration (MIC)and antibiotic susceptibility to clindamycin by using test_tube dilution and disc diffusion methods.PCR was used to detect the erm gene in Streptococcus uberis.We find that clindamycin has strong antibacterial activities.Comparision of erm (S.uberis)and ermS(S.sanguis)sequences showed 99%(750/757)conservation,which also suggests erm gene located on both plasmid and chromosome.

关 键 词：乳房链球菌 克林霉素 耐药基因 奶牛 

分 类 号：S852.611[农业科学—基础兽医学] S858.232.6[农业科学—兽医学]