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机构地区:[1]中山大学孙逸仙纪念医院妇产科,广东广州510120
出 处:《中国计划生育和妇产科》2014年第3期11-15,共5页Chinese Journal of Family Planning & Gynecotokology
摘 要:排卵功能障碍是导致女性不孕症的一个重要原因,最显著的特征是稀发排卵或无排卵。稀发排卵和无排卵除了引起月经紊乱和不孕不育,其远期危害也不容忽视。多囊卵巢综合征(polycystic ovary syndrome,PCOS)是临床工作中最常见的排卵障碍性疾病,病理生理改变持续存在,远期常引起一系列内分泌/代谢紊乱,如子宫内膜增殖症、子宫内膜癌、胰岛素抵抗、糖耐量受损、糖尿病、高血压、血脂代谢异常、代谢综合征、心血管疾病风险增加等。近20年来,PCOS的远期并发症得到了较为充分的研究,排卵障碍患者的远期健康状况和并发症防治等问题日益受到重视。Ovulatory dysfunction is an important cause of female infertility with mainly characteristics of oligo-ovulation and anovulation. In addition to causing menstrual disorders and infertility,the long-term complications of oligo-ovulation and anovulation can not be ignored. Polycystic ovary syndrome( PCOS) is the most common clinical ovulation disorders with persisting pathophysiological changes, which causes a series of endocrinic/metabolic disorders, such as endometrial hyperplasia, endometrial cancer, insulin resistance, impaired glucose tolerance, diabetes,hypertension,dyslipidemia,metabolic syndrome,an increased risk of cardiovascular disease,et al. During the past 20 years, the long - term complications of PCOS were obtained sufficient researches, the long - term health situations of ovulation disorders patients and prevention of the complications have been paid more attentions.
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