高效液相色谱-串联质谱法测定染发剂中11种苯胺和苯酚类染料  

Determination of 11 Kinds of Phenol and Aniline Dyes in Oxidative Hair Dyes by High Performance Liquid Chromatography-Tandem Mass Spectrometry

作　　者：邵超英[1] 秦婷[1] 孙多志[2] 刘峻[2] 邵玉婉[2] 

机构地区：[1]东华大学化学化工与生物工程学院,上海201620 [2]上海市质量监督检验技术研究院轻工与化工产品质量检验所,上海201114

出　　处：《分析化学》2014年第5期781-782,共2页Chinese Journal of Analytical Chemistry

摘　　要：1引言 在众多染发剂产品中,人工合成的氧化型染发剂由于染色效果好、色调丰富、颜色持久等优点,应用极为广泛。但这类染发剂多以芳香胺和/或酚类组分为有效成分,易引起人体过敏等不良反应,长期使用甚至可能导致＂三致＂。A method of simultaneous determination of the eleven phenol and aniline dyes in oxidative hair dyes by ultrasonic-assisted extraction and high performance liquid chromatography-tandem mass spectrometry was developed. The orthogonal and single-factor experiments were designed to and optimize the ultrasonic-assisted extraction conditions, and the samples were extracted using 10 mL of 5% methanol under the conditions of ascorbic acid as an antioxidant for 10 min. The gradient elution program and the electrospray ionization mode change were together used for the optimization of the measurements, and the determinations were completed by using the multi-reaction monitoring scan. The detection limits were 1. 15-9. 43 μg/g, the recoveries of spiked samples were 88. 0%-118. 1%. The method can be used to determine trace prohibited and restricted dyes in hair dyes.

关 键 词：氧化型染发剂 高效液相色谱-串联质谱法 苯酚类 染料 苯胺 测定 染色效果 人工合成 

分 类 号：O657.63[理学—分析化学] TQ658.34[理学—化学]