醒脑静注射液致22例不良反应文献分析  

Literature Analysis about Adverse Reactions to Xingnaojing injection in 22 Cases

作　　者：胡玉良[1] 曾聪彦[1] 

机构地区：[1]广州中医药大学附属中山市中医院,广东中山528400

出　　处：《亚太传统医药》2014年第11期85-87,共3页Asia-Pacific Traditional Medicine

基　　金：广东省中山市科技计划资助项目(20091A028)

摘　　要：目的:分析醒脑静注射液所致不良反应的特点和预防方法,促进合理用药。方法:检索1994-2013年国内医药学期刊报道应用醒脑静注射液致不良反应案例,并进行统计、分析。结果:醒脑静注射液所致不良反应与性别、年龄无关,与用法用量有关;其出现时间可发生于用药后的各个时间段,以30min内发生居多(13例,占59.1%),再次或反复用药后发生8例(占36.4%);临床主要表现为过敏反应,严重者可出现过敏性休克。结论:临床医师、药师应了解醒脑静注射液所致不良反应的规律和特点,加强临床用药监测,以减少不良反应的发生。Objective： To analyzie the features and protections of the ADRs associated with xingnaojing injection so as to improve the prational drug use. Methods：ADRs to xingnaojing injection in 22 cases, reported in domestic medical journals during 1994- 2013, were collected and analysed. Results：The ADRs to xingnaojing injection were independent of pationfs sex and age, dependent of the dosage and router of medication. The ADRs could occur at any time after medication. 13（59.1%） ADRs acured within 30min after injection, and 8 cases（36.4%） had ADRs at a second time or repeated injection. The clinical manifestations were various and manifested as allergic reaction or even allergic shock in severe cases. Conclusion ： Doctors and pharmacists should master the pat- tern and characteristics of ADRs induced by Xingnaojing injection,and strengthen monitoring on the use of it to reduce the incidence of ADR.

关 键 词：醒脑静注射液 不良反应 文献分析 

分 类 号：R969[医药卫生—药理学]