加味左金丸治疗肝胃不和型反流性食管炎临床观察  

Effect of Jiawei Zuojin Pills on Reflux Esophagitis with Liver-Stomach Disharmony Syndrome

作　　者：李奕升[1] 郭洪波[1] 罗辉娥 马厚蓉[1] 

机构地区：[1]深圳市龙岗区人民医院中心城社区健康服务中心,广东深圳518172

出　　处：《中国中医药信息杂志》2014年第6期35-37,共3页Chinese Journal of Information on Traditional Chinese Medicine

摘　　要：目的观察加味左金丸联合西药治疗肝胃不和型反流性食管炎的临床疗效。方法将90例患者随机分为观察组和对照组,每组45例。对照组予雷贝拉唑钠肠溶胶囊和多潘立酮片,观察组在对照组治疗基础上给予加味左金丸治疗,连用4周。观察2组患者的临床疗效?治疗前后的中医证候积分及胃镜改善效果。结果临床疗效比较,观察组总有效率为95.5%(43/45),对照组为93.3%(42/45),差异无统计学意义(P>0.05);观察组显效率为77.8%(35/45),对照组为57.8%(26/45),差异有统计学意义(P<0.05)。治疗后2组中医证候积分均有改善(P<0.001),观察组优于对照组(P<0.05)。胃镜下食管炎症改善程度比较,观察组总有效率为96.5%(43/45),对照组为77.8%(35/45),差异有统计学意义(P<0.05)。结论加味左金丸联合西药治疗反流性食管炎有较好的疗效。Objective To observe the clinical effect of Jiawei Zuojin Pills combined with western medicine on reflux esophagitis with liver-stomach disharmony syndrome. Methods Totally 90 cases were divided into observation group （45 cases） and control group （45 cases）. The control group was given rabeprazole sodium enteric-coated capsule and domperidone tablets, and the observation group was given Jiawei Zuojin Pills additionally for four weeks. The clinical effect, TCM syndrome score and endoscopic improvement were observed. Results The total effective rate of observation group was 95.5%（43/45）, control group was 93.3%（42/45）, with no significant difference between the two groups （P〉0.05）. The excellent rate of observation group was 77.8% （35/45）, control group was 57.8% （26/45）, with significant difference （P〈0.05）. TCM syndrome score was improved in both groups （P〈0.001）, and the degree of improvement in the observation group was better than control group （P〈0.05）. The total effective rate rate under endoscopic of observation group and control group was 96.5% （43/45） and 77.8% （35/45） respectively, with significant difference （P〈0.05）. Conclusion Jiawei Zuojin Pills combined with western medicine has obvious efficacy in treating reflux esophagitis with liver-stomach disharmony syndrome.

关 键 词：加味左金丸 反流性食管炎 肝胃不和 

分 类 号：R259.71[医药卫生—中西医结合]