重庆市2008～2012年无偿献血者HBsAg,ALT及抗HIV、抗HCV、抗TP抗体检测结果的分析  

A survey on test results of HBsAg,ALT and anti-HIV,anti-HCV,anti-TP antibodies among voluntary blood donors in Chongqing from 2008 to 2012

作　　者：程颖[1] 李维[1] 程燃[2] 

机构地区：[1]重庆市血液中心检验科,重庆400015 [2]重庆市中山医院检验科,重庆400014

出　　处：《国际检验医学杂志》2014年第10期1297-1298,1304,共3页International Journal of Laboratory Medicine

摘　　要：目的分析重庆市2008~2012年无偿献血者乙型肝炎病毒表面抗原（HBsAg）,丙氨酸氨基转移酶（ALT）及抗丙型肝炎病毒（HCV）、抗人类免疫缺陷病毒（HIV）、抗梅毒螺旋体（TP）抗体检测结果,为招募低危无偿献血者,减少血液报废提供依据。方法选择2008~2012年于重庆市血液中心接受酶联免疫吸附测定（ELISA）筛查的无偿献血者的血液标本551 133例,检测其HBsAg,ALT及抗HIV、抗HCV、抗TP抗体。采用实验室信息管理系统ITSWELL对检测结果进行读取、保存、汇总,并判断标本是否合格。结果共计检出不合格标本37 534例（6.81%）,其中,HBsAg,ALT及抗HCV、HIV、TP抗体不合格率分别为1.10%、3.79%、0.51%、0.33%、1.08%。结论加强血液检测试剂筛选及无偿献血者队伍的建设将有助于临床的输血安全。Objective To analyze the test results of hepatitis B virus surface antigen（HBsAg） ,alanine aminotransferase（ALT） and anti-hepatitis C virus （HCV） ,anti-human immunodeficiency virus （HIV） ,anti-treponema pallidum （TP） antibodies among voluntary blood donors ,and to provide basis for recruiting low-risk voluntary blood donors and reducing blood abandonment . Methods 551 133 blood samples derived from voluntary blood donors which had accepted enzyme-linked immunosorbent assay （ELISA） screening in Chongqing Blood Center from 2008 to 2012 were collected and were subject to HBsAg ,ALT and anti-HIV , anti-HCV ,anti-TP antibodies detection .Laboratory information management system ITSWELL was employed to read ,save and gather the test results ,and whether the samples were qualified was determined .Results Total of 37 534（6 .81% ） substandard blood samples were detected .Among them ,the substandard rates of HBsAg ,ALT and anti-HCV ,anti-HIV ,anti-TP antibodies were 1 .10% ,3 .79% ,0 .51% ,0 .33% and 1 .08% ,respectively .Conclusion Strengthening the screen of blood detection reagents and building the team of voluntary blood donors will contribute to the safety of clinical blood transfusion .

关 键 词：肝炎表面抗原 乙型 肝炎抗体 丙型 血液筛查 重庆 

分 类 号：R446.6[医药卫生—诊断学]