血必净注射液对感染性疾病的临床应用研究进展  

Research progresses of Xuebijing injection clinical application of inflammatory diseases

作　　者：张玮[1] 朱艳娜[1] 王艳[1] 

机构地区：[1]大连医科大学附属第一医院药学部,辽宁大连116011

出　　处：《时珍国医国药》2014年第5期1189-1191,共3页Lishizhen Medicine and Materia Medica Research

基　　金：辽宁省教育厅科学研究一般项目立项项目(No.L2013355)

摘　　要：血必净注射液是一种中药复方注射液,主要有效成分有红花、赤芍、川芎、丹参、当归等,其抑制炎性因子如白细胞介素、肿瘤坏死因子等表达,从而产生抗炎作用;也可以抑制炎症反应过程中的转录因子的活性,保护机体重要器官。自面世以来,在临床上广泛应用于脓毒症、多器官功能障碍综合征等,其与血必净注射液抑制炎性反应有关。Xuebijing （XBJ） injection is a traditional Chinese medicine （TCM） injection. The injection combines five TCMs, including Carthami Flos, Paeoniae Radix Rubra, Chuanxiong Rhizoma, Salviae miltiorrhizae and Angelicae Sinensis Radix. It plays an anti - inflammatory effect by inhibiting interleukins, tumor necrosis factor and inhibiting the activity of important transcription factors, thus plays a protective role for vital organs. XBJ is widely used in the treatment of sepsis and multiple organ dysfunction syndromes; it has a close relationship with XBJ injection and the inflammatory response.

关 键 词：血必净注射液 炎性反应 

分 类 号：R289.5[医药卫生—方剂学]