非过敏性鼻炎伴嗜酸性粒细胞增多症鼻通气主观症状与鼻通气功能相关性研究  

Study on the correlation between subjective symptoms and function of nasal ventilation in nonallergic rhinitis with eosinophilia syndrome

作　　者：阳光[1] 杨长亮[1] 黄鹏[1] 姚行齐[1] 

机构地区：[1]广州军区武汉总医院耳鼻咽喉科,湖北省武汉430070

出　　处：《中国基层医药》2014年第10期1458-1460,共3页Chinese Journal of Primary Medicine and Pharmacy

摘　　要：目的：对非过敏性鼻炎伴嗜酸性粒细胞增多征（ NARES）患者鼻通气主观症状与鼻通气功能相关性进行分析，从而为其临床诊断提供依据。方法选择NARES患者44例作为NARES组，并以同期健康体检者50例作为对照组。比较两组鼻总阻力值（TNR）、最小横截面积（MCA），并对NARES患者主观症状及客观检测指标进行Pearson或Spearman相关性分析。结果收缩前，NARES组在75 Pa和150 Pa TNR均高于健康对照组（Mann-Whiteny Z＝7．365、8．125，均P＜0．05）；收缩后，两组75 Pa和150 Pa TNR差异、MCA差异、NARES 8个主观症状与7个客观指标相关性分析，差异均无统计学意义（均P＞0．05）。结论非过敏性鼻炎伴嗜酸性粒细胞增多征患者鼻通气功能与主观症状之间相关性不明显，临床诊断应全面进行，以防漏诊和误诊。Objective To analyze the correlation between subjective symptoms and function of nasal ventila-tion in nonallergic rhinitis with eosinophilia syndrome （ NARES） ,in order to provide the basis for the clinical diagno-sis.Methods 44 patients with NARES were selected as the NARES group ,and 50 healthy people were selected as the control group at the same time .The total nasal resistance （ TNR ） , MCA of the two groups were compared , and Pearson or Spearman correlation was used to analyze the subjective symptoms and objective test indexes in patients with NARES.Results Before contraction,the TNR values of NARES group in 75Pa and 150Pa were higher than those of the control group （Mann-Whiteny Z=7.365,8.125,all P〈0.05）.After contraction,the differences of TNR values in 75Pa and 150Pa,MCA,the correlation analysis in 8 subjective symptoms and 7 objective index of NARES had no statistically significant differences between the two groups （ all P 〉0.05）.Conclusion The correlation between subjective symptoms and function of nasal ventilation in NARES patients is not obvious .Clinical diagnosis should be comprehensive ,in case of missed diagnosis and misdiagnosis .

关 键 词：鼻炎 嗜酸性粒细胞增多 

分 类 号：R765.21[医药卫生—耳鼻咽喉科] R557.3[医药卫生—临床医学]