高糖高脂对肾小球细胞影响的研究进展  

Research progress in impact of high glucose and hyperlipidemia on glomerular cells

作　　者：周素娴[1] 

机构地区：[1]桂林医学院附属医院内分泌科,桂林545005

出　　处：《新医学》2014年第5期286-289,共4页Journal of New Medicine

基　　金：广西科技厅青年基金(2011GXNSFB018108);广西中医药管理局(GZKZ1146)

摘　　要：糖尿病肾病(DN)是糖尿病的常见并发症,已成为导致终末期肾病的重要因素之一。高糖和高脂与DN的发生发展密切相关。肾脏的固有细胞包括肾小球毛细血管内皮细胞、肾小球系膜细胞、足细胞、肾小管上皮细胞和间质成纤维细胞,DN的发生发展与高糖、高脂对固有细胞的影响有关。Diabetic nephropathy （DN）is a common complication of diabetes mellitus and has be-come an important cause of end-stage renal disease. High glucose and hyperlipidemia are closely related to the development of DN.Renal inherent cells include glomerular capillary endothelial cells,glomerular mesangial cells,podocyte,renal tubular epithelial cells and stromal fibroblasts.The development and progression of DN is related to the influence of high glucose and hyperlipidemia on renal inherent cells.

关 键 词：高糖高脂 糖尿病肾病 内皮细胞 系膜细胞 足细胞 

分 类 号：R587.2[医药卫生—内分泌] R692[医药卫生—内科学]