抗菌药物治疗妊娠中期阴道炎的疗效及与早产的关系探讨  

Curative effect of antibiotic treatment for inflammation of vagina in mid-trimester and relation to premature delivery

作　　者：王静[1] 李苗[1] 吴兰芬[1] 

机构地区：[1]杭州市余杭区妇幼保健院妇产科,浙江杭州311100

出　　处：《中华医院感染学杂志》2014年第11期2816-2817,2820,共3页Chinese Journal of Nosocomiology

基　　金：浙江省杭州市余杭区科学技术局计划基金项目(2011-医药卫生-13)

摘　　要：目的探讨抗菌药物治疗妊娠中期阴道炎症的疗效及其与早产的关系,减少早产的发生。方法根据孕妇是否同意临床抗菌药物治疗的意愿,将312例孕妇分为使用药物治疗的196例为观察组,拒绝药物治疗的116例为对照组,观察两组孕妇的临床疗效、早产以及随访评价生活质量,采用SPSS17.0统计软件进行数据统计分析。结果治疗后观察组孕妇治愈率90.82%,优于对照组的56.25%,差异有统计学意义(P<0.01);孕妇早产率观察组为2.55%,对照组18.97%,两组差异有统计学意义(P<0.01),分娩出院后观察组产妇各项生活质量指标均优于对照组产妇,差异有统计学意义(P<0.05)。结论对于妊娠中期阴道炎症孕妇予以抗菌药物治疗,可有效预防早产的发生,改善母儿预后。OBJECTIVE To discuss the antibiotic effect on asymptomatic vaginitis in mid-trimester of pregnancy and the relation to premature delivery, so as to prevent premature delivery. METHODS Based on the wiliness of using clinical antimicrobial agents, a total of 312 pregnant women were divided into 196 cases of using as observation group and 116 cases of refusing to use as control group. The clinical effects, premature delivery and follow-up evaluation of the quality of life were under observation, and the data were analyzed by SPSS. RESULTS After treatment, the cure rate of observation group was 90.82%, higher than that in control group 56.25%, and the difference had statically significant （P〈0.01）. In observation group, the premature delivery rate was 2.55M, which was lower than that of the control group 18.97%, and the difference had statically significant （P〈0.01）. After discharge the various indicators of the quality of life were better than the control group, and the difference was statically significant （P 〈 0. 05）. CONCLUSIONS Pregnant women with inflammation of vagina in midtrimester should be treated with standard therapy in antibacterial agents, which could prevent remature delivery and improve prognosis of both mother and fetus.

关 键 词：阴道炎症 早产 围产期 抗菌药物 

分 类 号：R711.31[医药卫生—妇产科学]