检测子痫前期患者尾加压素Ⅱ及内皮型一氧化氮合酶的临床意义研究  

Clinical significance of detecting preeclampsia patients＇ urotensin Ⅱ and endothelial nitric oxide synthase

作　　者：惠薇[1] 

机构地区：[1]南方医科大学附属何贤纪念医院产科,广州511400

出　　处：《国际医药卫生导报》2014年第12期1674-1675,共2页International Medicine and Health Guidance News

基　　金：番禺区科技计划项目（2012-Z-03-46）

摘　　要：目的探讨检测子痫前期孕妇血中尾加压素Ⅱ（UⅡ）与内皮型一氧化氮合酶（eNOS）含量的临床意义。方法选择我院产科收治的子痫前期孕妇30例（实验组）及普通孕妇30例（对照组），采用ELISA法分别检测2组孕妇血中的尾加压素Ⅱ及内皮型一氧化氮合酶的含量水平值，并对检测结果进行对比分析。结果实验组尾加压素Ⅱ含量水平值（3．27±1．12）μmol／L明显高于对照组孕妇（1．91±0．39）μmol／L；对照组内皮型一氧化氮合酶含量水平值（89．33±25．79）μmol／L明显低于实验组（125．67±34．36）μmol／L，差异均有统计学意义（P〈0．05）。结论通过检测孕妇血中eNOS与UⅡ水平可反映该病的发展情况，可作为该病的辅助指标，为临床早期监控及治疗提供重要的价值。Objective To investigate the clinical significance of detecting urotensin Ⅱ （UⅡ） and endothelial nitric oxide synthase （eNOS） in preeclampsia in pregnant women. Methods 30 pregnant women with preeclampsia （experimental group） and 30 normal pregnant women （control group） were selected from our hospital. UⅡ and eNOS were detected by ELISA. The detection results were compared and analyzed. Results The levels of UⅡ and eNOS were （3.27 ±1.12） μmol/L and （125.67 ± 34.36）μ mol/L in the experimental group and were （1.91 ± 0.39） pmol/L and （89.33±25.79） μ mol/L in the control group, with statistical differences. Conclusions Detecting maternal serum eNOS and U Ⅱ levels can reflect the development situation of the disease and be used as an auxiliary index of this disease and is valuable for the disease＇ s early monitoring and treatment.

关 键 词：子痫前期 尾加压素Ⅱ 内皮型一氧化氮合酶 

分 类 号：R714.244[医药卫生—妇产科学]