178例药源性眼部损害文献分析  

作　　者：李莉[1] 于浩[2] 刘伟红[3] 

机构地区：[1]威海市文登中心医院药学部,264400 [2]威海市文登中心医院普外科,264400 [3]威海市文登中心医院妇科,264400

出　　处：《国际医药卫生导报》2014年第12期1782-1784,共3页International Medicine and Health Guidance News

摘　　要：目的探讨药物性眼部损害的临床特点。方法回顾性分析2000年至2013年CNKI载录的178例药源性眼部损害的相关临床病历资料文献，对文献中患者的年龄、性别、原患疾病、用药情况、临床表现等数据进行统计分析。结果178例药源性眼部损害案例男102例，女76例，主要以口服和静脉滴注为主。共涉及10大类药物112个品种，抗微生物药最多有54例。结论药源性眼部损害的致病药物种类繁多，临床应加强对重点药物的监测，避免和减少药源性眼部损害的发生。Objective To discuss the characteristics of drug-induced eye disorders.Methods 178 cases of drug-induced eye disorders in CNKI from 2000 to 2013 were retrospectively analyzed and the data of age,gender,primary diseases,the kinds and categories of drugs,clinical manifestation were investigated.Results Among the total 178 cases,the ratio of male (102 cases) and female (76 cases) was 1.34:1.00.Oral and intravenous administration were the main routes.There were 178 cases of drug-induced eye disorders caused by 112 kinds of drugs.54 cases were induced by anti-microbial agents (accounting for 30.34％).Conclusion The causative drugs were diverse.Related drugs should be monitored in clinical practice to avoid or decrease drug-induced eye disorders.

关 键 词：药源性眼部损害 抗微生物药 药物不良反应 

分 类 号：R595.3[医药卫生—内科学]