正交试验优选白芨胶的提取工艺  

Optimization of Extraction Technology of Bletilla striata Gum Gastric Mucoadhesive Powder by Orthogonal Test

作　　者：周忠东[1] 陈劲柏[1] 王建平[2] 

机构地区：[1]绍兴市中医院,浙江绍兴312000 [2]浙江省中医院,杭州310006

出　　处：《中国药房》2014年第23期2141-2142,共2页China Pharmacy

摘　　要：目的:优选白芨胶的提取工艺。方法:以乙醇浸泡浓度、加热回流时间、加热回流温度为因素,以白芨胶收率为指标进行L9(34)正交试验。结果:白芨胶的最佳提取工艺为100 ml 70%乙醇溶液浸泡4 h,80℃加热8 h,白芨胶收率为33.7%。结论:该提取工艺稳定、可行,避免了有机溶剂的引入,可为工业生产提供依据。OBJECTIVE： To optimize the extraction technology of Bletilla striata gum gastric mucoadhesive powder of Corydalis turtschaninovii and Melia toosendan. METHODS： The preparation technology of B. striata was optimized by L9（3^4） orthogonal technology with ethanol soaking concentration, heating reflux duration and heating reflux temperature as factors using the yield of B. striata gum as index. RESULTS： The optimal preparation technology was as follows： soaking in 100 ml 70% ethanol for 4 h, at 80℃, heating for 8h, yield of B. striata 33.7%. CONCLUSIONS： The preparation technology of B. striata gum gastric mucoadhesive powder is scientific to avoid the introduction of organic solvent, and the trial provides reference for industrial production.

关 键 词：白芨胶 生物黏附给药系统 正交试验 

分 类 号：R283[医药卫生—中药学] R624[医药卫生—中医学]