不同温度对比剂与CT血管造影不良反应间的关系研究  

Study of the adverse drug reactions of iodinated contrast agent in different temperatures after CT angiography

作　　者：胡辉军[1] 陈娇霞[2] 邓虹[1] 张翔[1] 沈君[1] 

机构地区：[1]中山大学孙逸仙纪念医院放射科,广州510120 [2]中山大学孙逸仙纪念医院内科门诊,广州510120

出　　处：《岭南现代临床外科》2014年第3期308-310,共3页Lingnan Modern Clinics in Surgery

基　　金：广东省医学科研基金(编号:B2013122)

摘　　要：目的探讨注射不同温度的碘对比剂进行CT血管造影时受检者不良反应（ADR）的发生。方法将3200例进行多层螺旋CT血管造影的受检者随机分为常温组（n=1520）和加温组（n=1680），常温组与加温组分别在室温下（18℃-22℃）与将对比剂放入恒温箱加热至37℃后进行血管造影，观察两组受检者的外渗和过敏样反应的发生率。结果静脉注射碘普罗胺（优维显370）进行血管造影时，加温组的外渗和过敏样反应的发生率明显低于常温组。结论加热碘对比剂能明显降低不良反应的发生，值得大力推广应用。Objective To investigate the relationship between iodinated contrast agent in different temperatures with incidence of adverse drug reactions （ADR） after CT angiography. Methods 3200 testers who examined with multi detector CT angiography were randomly divided into two groups, normal temperature group（n=1520） and heating group（n=1680）, which performed CT angiography with contrast agent of home temperature and heated to 37 in the constant temperature box. The incidence of exosmose and anaphylactoid reaction after contrast agent injection were detected. Results The incidence of exosmose and anaphylactoid reaction in heating group was lower than that of normal temperature group after iopromide intravenous injection. Conclusion It is worthy of being widely popularized in clinical application with heating of iodinated contrast agent which may reduce the incidence of ADR.

关 键 词：CT血管造影 不良反应 外渗 过敏样反应 

分 类 号：R604[医药卫生—外科学] R445.3[医药卫生—临床医学]