Fmr1基因敲除小鼠生长发育指标的测定分析  

Characterization of Growth Performance in Fmr1 Knockout Mice

作　　者：叶炳飞[1] 黄月玲[1] 戴丽军[1] 

机构地区：[1]广州医科大学实验动物中心,广东广州510182

出　　处：《广东第二师范学院学报》2014年第3期61-63,共3页Journal of Guangdong University of Education

基　　金：广东省科技计划重点攻关项目(200560302004;2009B060300018)

摘　　要：挑选清洁级10周龄Fmr1基因敲除小鼠20只(雌、雄各半),采取1∶1同居,全同胞兄妹近交繁殖,测定子代生长发育指标,并进行统计分析,为Fmr1基因敲除小鼠的应用研究提供基础数据.结果显示,清洁级Fmr1基因敲除小鼠初生体重、体长分别为1.25±0.21g、38.99±1.74mm;离乳体重体长分别为8.17±2.26g、122.81±11.42mm;60日龄时体重体长分别为22.93±2.93g、180.19±7.46mm.To characterize the growth performance of Fmrl knockout mice, 20 seed mice （10-weeks age of seed mice） were chosen and monogamously mated. The parameters of growth performance were analyzed. The results indicated that the average weight and length of newborns is 1.25±0.21 g, 38.99±1.74 mm; by 3rd week, the average weight and length is 8.17±2.26 g, 122.81±11.42 mm; and by 8th week, the average weight and length is 22.93±2.93 g, 180.19±7.46 mm.

关 键 词：基因剔出 FMR1 小鼠 生长发育指标 

分 类 号：Q953[生物学—动物学]