舒血宁联合速避凝治疗原发性肾病综合征的效果分析  

An analysis on the effects of shuxuening combined with fraxiparine in the treatment of primary nephrotic syndrome

作　　者：卜爽剡 吕忠民 俞燕[2] 

机构地区：[1]浙江省东阳市人民医院肾内科,浙江东阳322100 [2]南通大学附属医院肾内科,江苏南通226001

出　　处：《中国现代医生》2014年第16期54-57,共4页China Modern Doctor

基　　金：江苏省卫生厅面上项目(H201016)

摘　　要：目的探讨舒血宁联合速避凝治疗原发性肾病综合征（PNS）的临床疗效。方法以2012年3月～2013年3月东阳市人民医院收治的84例PNS患者为研究对象，随机分为两组，对照组予速避凝治疗，实验组予舒血宁联合速避凝治疗，对比两组的临床治疗效果。结果实验组总有效率为92．85％，对照组76．19％，两组比较差异有统计学意义（P〈0．05）；两组治疗后凝血指标、肾功能水平以及血脂水平比较差异有统计学意义（P〈0．05）；实验组不良反应发生率为16．67％，对照组为38．10％，两组比较差异有统计学意义（P〈0．05）。结论舒血宁联合速避凝治疗能有效改善PNS患者的血液流变学指标和血脂水平，可以有效延缓PNS的病情恶化，值得临床推广。Objective To explore the clinical effects of shuxuening combined with fraxiparine in the treatment of primary nephrotic syndrome （PNS）. Methods Eight-four patients who were admitted to the Dongyang people＇s hospital from March 2010 to March 2013 were selected as subjects and randomly assigned into two groups. The control group was administered fraxiparine while the experimental group was administered Shuxuening combined with fraxiparine. The clinical effects between the two groups were then compared. Results The total effective rate in experimental group was 92.85%, and that in control group was 76.19%, the difference between two groups was statistically significant（P〈0.05）; The differences of coagulation indices, renal functions and blood lipid levels between the two groups after the treatment were all statistically significant （P〈0.05）; The incidence of adverse effects in experimental group was 16.67%, and that in control group was 38.10%, The Difference was statistically significant （P〈0.05）. Conclusion Shuxuening combined with fraxiparine helps effectively improve hemorheological indices and blood lipid level for patients with PNS and effectively delay the exacerbation of PNS, which is worthy of clinical promotion.

关 键 词：舒血宁 速避凝 原发性肾病综合征 

分 类 号：R692[医药卫生—泌尿科学]