平顶山地区无偿献血者红细胞血型不规则抗体检测分析  

Detection and analysis of the irregular antibodies of voluntary blood donors in Pingdingshan region

作　　者：杜玮璐 杜红梅 马红 李召选 

机构地区：[1]平顶山市中心血站,河南平顶山467000

出　　处：《中国输血杂志》2014年第5期516-517,共2页Chinese Journal of Blood Transfusion

摘　　要：目的探讨本地区无偿献血人群中红细胞血型不规则抗体的分布特点，为临床科学安全供血提供依据。方法采用盐水介质法和聚凝胺法对本站2011年1月－2012年12月间85541名（次）献血者进行不规则抗体筛查、鉴定。结果85541名（次）献血者中检出不规则抗体阳性者13l例，阳性率0．15％，分别为抗-D 11例，抗-E 7例，抗-M 33例，抗－N5例，抗-P1 21例，冷抗体25例，不明抗体29例，其中不规则抗体阳性者男55例（0．06％），女76例（0．09％），男女相比差异有统计学意义。结论本地区无偿献血人群中红细胞血型不规则抗体阳性率占一定比率，为保证临床输血的安全性和有效性，对献血者进行不规则抗体的检测，对于减少因输入含不规则抗体血液而引起的输血反应具有重要意义。Objective To investigate the distribution of irregular antibodies in Pingdingshan region and provide evidence for safe blood supply in clinical application. Methods Using saline method and polvbrene method to screening the irregular antibody in 85 541 samples from January in 2011 to December in 2012. Results 131 blood donors are detected with irregular antibody,with the positive rate of 0.15% ,that is 11 cases of anti-D,7 cases of anti-E,33 cases of anti-M,5 cases of anti-N, 21 cases of anti-P1,25 cases of cold antibody, 29 cases of unknown antibody, respectively. Among those irregular antibody positive samples,55 cases were from men （0.06%）, and female 76 cases （0.09%） , which showed significant difference. Conclusion The positive rate of irregular antibody has taken some proportions in this area. The detection of irregular antibodies in blood donors is important to ensure the safety and effectiveness, of clinical blood transfusion.

关 键 词：无偿献血 红细胞血型 不规则抗体 

分 类 号：R457.11[医药卫生—治疗学]