姜黄中倍半萜类化学成分的研究  

Study on the sesquiterpene constituents of Curcuma longa

作　　者：张俊侠[1,2] 肖云川[2] 刘淼[2] 冉坚[2] 许浩然[2] 黄静[2] 

机构地区：[1]成都学院,四川成都610106 [2]四川大学华西药学院,四川成都610041

出　　处：《华西药学杂志》2014年第3期260-262,共3页West China Journal of Pharmaceutical Sciences

摘　　要：目的研究姜黄的化学成分。方法采用柱色谱法分离纯化单体化合物并应用NMR技术鉴定其化学结构。结果分离纯化得到了3个化合物,分别鉴定为:6-(4,5-dihydroxy-4-methyl-cyclohex-2-en-1-yl)-2-hydroxy-2-methylheptan-4-one(Ⅰ),(6S)-2-methyl-6-[(1R,5S)-(4-methene-5-hydroxyl-2-cyclohexen)-2-hepten-4-one](Ⅱ)和bisacurone B(Ⅲ)。结论化合物Ⅰ为新天然产物。OBJECTIVE To study the chemical constituents of Curcuma longa L. METHODS The chemical constituents were isolated and purified by column chromatography. Their structures were identified by spectral analysis. RESULTS Three compounds were isolated and their structures were identified as 6 - （4,5 -dihydroxy -4 - methylcyclohex -2 - en - 1 - yl） -2 - hydroxy -2 - methyl - heptan - 4 - one （ 1 ） , （6S） - 2 - methyl - 6 - [ （ 1 R, 5S） - （ 4 - meth - ene - 5 - hydroxyl - 2 - cyclohexen）] - 2 - hepten - 4 - one（ Ⅱ ） and bisacurone B （ Ⅲ ）. CONCLUSION Compound Ⅰ was isolated from the nature for the first time.

关 键 词：姜科 姜黄 Bisabolomin 化学成分 倍半萜 

分 类 号：I284[文学—中国文学]