经尿道电切术联合丝裂霉素膀胱灌注治疗腺性膀胱炎的疗效分析  

Analysis on the efficiency of transurethral resection combined with intravesical mitomycin perfusionon in the treatment of cystitis glandular

作　　者：孙学国[1] 姜从梅[2] 

机构地区：[1]湖北省房县人民医院心胸泌尿外科,湖北十堰442100 [2]湖北省房县人民医院门诊西药房,湖北十堰442100

出　　处：《实用临床医药杂志》2014年第5期118-121,共4页Journal of Clinical Medicine in Practice

基　　金：中国高校医学期刊临床专项资金(11321695)

摘　　要：目的探讨经尿道电切术联合丝裂霉素膀胱灌注治疗腺性膀胱炎的临床疗效。方法将本院收治的腺性膀胱炎患者随机分为观察组和对照组,每组35例。经尿道电切术后,对照组给予盐酸吡柔比星膀胱灌注,观察组给予盐酸吡柔比星、丝裂霉素进行膀胱灌注。采用生活质量评分量表对2组患者生活质量进行评分,并比较灌注后的临床疗效。结果观察组总有效率有高于对照组的趋势,但差异无统计学意义;观察组各项生活质量评分均显著高于对照组,而不良反应发生率明显低于对照组,差异均有统计学意义。结论经尿道电切术联合丝裂霉素膀胱灌注治疗腺性膀胱炎疗效确切,不良反应发生率低,患者各项生活质量均有提高,值得临床推广。Objective To explore the clinical effect of transurethral resection combined with intravesical mitomycin perfusionon in the treatment of cyslitis glandular （CG）. Methods A total of 70 patients with CG in our hospital were randomly divided into control group （ n = 35） and observation group （ n = 35）. After transurethral resection, the control group was given pirarubicin hydrochloride by perfusion of bladder, while the observation given pirarubicin hydrochloride combined with mitomycin by perfusion of bladder. The quality of life was evaluated by Quality of Life Scale in both groups, and clinical effects were compared. Results The difference was not significant though the overall response rate in observation group was slightly higher than that in the control group; The score of different items of quality of life in the obeservation group was evidently higher, but the incidence of adverse reactions was markedly lower in the observation group than that in the control group, and the differences was statistical significant. Conclusion Transurethral resection combined with intravesical mitomycin perfusion is effective in treating CG with low incidence of adverse reactions and high quality of life for patients, so it is worthy of being widely promoted in clinic.

关 键 词：腺性膀胱炎 经尿道电切术 丝裂霉素 盐酸吡柔比星 

分 类 号：R694[医药卫生—泌尿科学]