胃管注入解磷啶及甘露醇应用于有机磷农药中毒的临床观察及护理  

Clinical observation and nursing of organophosphorus pesticide poisoning with the treatment of pralidoxime and mannitol injection through stomach tube

作　　者：石咏梅[1] 尤静[1] 张小芹[1] 石红梅[1] 

机构地区：[1]江苏省泰兴市人民医院急诊中心,江苏泰兴225400

出　　处：《实用临床医药杂志》2014年第6期32-34,共3页Journal of Clinical Medicine in Practice

摘　　要：目的探讨解磷啶应用于有机磷农药中毒的用药途经,观察其临床效果,并探讨如何做好临床护理。方法将60例有机磷农药中毒患者随机分为观察组32例和对照组28例,对照组给予常规洗胃、阿托品化、解磷啶注射、补液、对症治疗及护理等,观察组在上述治疗的基础上,于洗胃管中注入解磷啶(或氯磷啶)及甘露醇,比较2组治疗的临床效果。结果观察组阿托品用量、反跳人数显著少于对照组(P<0.01),而达阿托品化时间、住院时间、治愈率、病死率等方面均优于对照组(P<0.05)。结论及早于洗胃管中注入解磷啶(或氯磷啶)及甘露醇,可明显提高有机磷农药中毒的抢救成功率。Objective To explore the treatment approach of organophosphorus pesticide poisoning and to observe its clinical effect and to explore the methods of clinical nursing. Methods 60 patients with organophosphorus pesticide poisoning were randomly divided into observation group with 32 patients and the control group with 28 patients. The control group was given routine gastric lavage, atropinization, pralidoxime injection, rehydration, symptomatic treatment and nursing while the observation group was injected pralidoxime and mannitol in the lavage tube （or Pyridinealdoxime methochloride） based on the treatment of control group. The treatment effect of two groups were compared. Results Atropine dosage and bounce in the observation group was ob- viously less than that in the control group （P〈 0.01）. Effectivness time of atropine, hospitaliza- tion time and curative rate were better than that in the control group （P 〈 0.05）. Conclusion Early lavage tube injection of pralidoxime and mannitol （or Pyridinealdoxime methochloride） can significantly improve success rate of organophosphorus pesticide poisoning of patients.

关 键 词：有机磷农药中毒 解磷啶 甘露醇 胃管注入 护理 

分 类 号：R472.2[医药卫生—急诊医学]