血清微量元素及外周血T淋巴亚群与反复呼吸道感染患儿的关系  

Correction between the serum trace elements,peripheral blood T lymphocyte subsets and children with recurrent respiratory tract infection

作　　者：潘晓洁[1] 刘红仙 梁敏[2] 

机构地区：[1]云南省昆明市儿童医院医务科,云南650228 [2]云南省昆明市官渡区妇幼保健中心,云南650200

出　　处：《实用临床医药杂志》2014年第7期51-53,共3页Journal of Clinical Medicine in Practice

摘　　要：目的探讨血清微量元素及外周血T淋巴亚群与反复呼吸道感染患儿的关系。方法选取2011年9月—2013年7月本院诊治的66例反复呼吸道感染患儿为观察组,同期66名健康检查示健康的儿童为对照组,比较2组儿童的清微量元素及外周血T淋巴亚群水平,以及观察组上呼吸道与下呼吸道感染、发作期及缓解期的检测结果,对上述指标与反复呼吸道感染的关系进行探讨。结果观察组血清Zn+、Fe3+、Mg2+及CD3+、CD4+、CD4/CD8均低于对照组,血清Cu2+及CD8+均高于对照组,下呼吸道感染及发作期患儿的检测结果差于上呼吸道感染及缓解期患儿,经分析,血清微量元素及外周血T淋巴亚群指标均与本病有密切的关系,差异均有统计学意义,P均<0.05。结论反复呼吸道感染患儿的血清微量元素及外周血T淋巴亚群呈现异常的状态,这些指标均与疾病有着密切的关系。Objective To explore the correction between serum trace elements, peripheral blood T lymphocyte subsets and children with recurrent respiratory tract infection. Methods 66 children with recurrent respiratory tract infection were selected and designed as observation group, and 66 children with health examination were designed as control group. Serum trace elements and peripheral blood T lymphocyte subsets of two groups were compared, and the detection results of observation group with upper respiratory tract infection and lower respiratory tract infection, at the stage of attack and catabasis were compared as well. Results The serum Zn ＋ , Fe3 ＋ , Mg2 ＋ and CD3 ＋ , CD4 ＋ , CD4/CD8 of observation group were significantly lower than those of control group, while serum Cu2 ＋ and CD8 ＋ were higher than those of control group. Detection results of observation group with lower respiratory tract infection and at the stage of attack were worse than those of children with upper respiratory tract infection and at the stage of catabasis. Serum trace elements and peripheral blood T lymphocyte subsets was closely correlated with the disease （ all P 〈 0.05）. Conclusion Serum trace elements and peripheral blood T lymphocyte subsets of children with recurrent respiratory tract infection are abnormal, and these indexes are closely correlated with the disease.

关 键 词：血清微量元素 外周血T淋巴亚群 反复呼吸道感染 

分 类 号：R725.6[医药卫生—儿科]