经皮内镜下胃造口管及鼻饲管在克罗恩病肠内营养支持中的疗效比较  

Effect comparison between percutaneous endoscopic gastrostomy and nasogastric feeding tube in enteral nutrition treatment of patients with Crohn's disease

作　　者：赵晓辉[1] 洪明[1] 路晓钦[1] 张耘[1] 何种林 常清[1] 

机构地区：[1]重庆市第九人民医院普外一科,重庆400700

出　　处：《实用临床医药杂志》2014年第7期124-126,共3页Journal of Clinical Medicine in Practice

基　　金：创伤;烧伤与复合伤国家重点实验室2011(2012);年度开放基金课题(SKLKF201102)

摘　　要：目的比较经皮内镜下胃造口管(PEG)及鼻饲管在克罗恩病肠内营养支持中的疗效。方法分析2007年1月—2013年1月在本院接受治疗的45例克罗恩病合并营养不良患者的临床资料,并分为PEG组24例和鼻饲组21例。结果 PEG组患者管饲并发症发生率为16.67%,显著低于鼻饲组的47.62%,差异有统计学意义(χ2=5.007,P=0.025)。治疗前2组患者相关营养学指标比较差异无统计学意义;治疗后2组患者在血白蛋白、前白蛋白、上臂围、上臂肌围、三头肌皮褶厚度及BMI上比较差异均无统计学意义(P>0.05);治疗后1个月,2组患者IBDQ均较同组治疗前显著升高(P<0.05),且鼻饲组治疗后IBDQ显著低于PEG组(P<0.05)。结论在克罗恩病的肠内营养支持中,PEG途径安全、有效,较传统的鼻饲途径具有管饲并发症发生率低、生活质量高等优势。Objective To compare the clinical efficacy my（PEG） and nasogastric feeding tube in the treatment of Crohn of percutaneous endoscopic gastrosto＇ s disease patients with malnutrition. Methods Clinical materials of 45 patients underwent enteral nutrition for CD from 2007 to 2013 were analyzed, and they were divided into PEG group （n = 24） and nasogastric feeding group （n = 21 ） Results The rate of tube-associated complications was 16. 67% in the PEG group, which was significantly lower than 4 7 . 6 2 % in the nasogastric feeding group （ χ2 = 5 . 0 0 7 , P = 0 . 0 2 5 ） . There was no significant difference of nutrition improvement between the two group （ P 〉 0.05 ）. One month after treatment, IBDQ score in the PEG group was significantly higher than that in the nasogastric method for CD feeding patients group （ P 〈 0.05 ）. Conclusion PEG is a safe, effective and comfortable who need to be treated with a long-term enteral nutrition.

关 键 词：克罗恩病 肠内营养 管饲 并发症 

分 类 号：R459.3[医药卫生—治疗学]