2009年-2011年沈阳地区手足口病病原检测分析  

Etiology study on hand,foot and mouth disease in Shenyang from 2009 to 2011

作　　者：刘娜[1] 董雪[1] 李欣[1] 张国斌[1] 李继耀[1] 高丹[1] 

机构地区：[1]沈阳市疾病预防控制中心,辽宁沈阳110031

出　　处：《中国卫生检验杂志》2014年第10期1471-1473,共3页Chinese Journal of Health Laboratory Technology

摘　　要：目的通过PCR检测了解2009年-2011年沈阳地区手足口病的病原学特征,为手足口病的防治工作提供科学依据。方法分别收集2009年-2011年手足口病粪便标本123份、264份及142份用RT-PCR进行鉴定。结果 2009年-2011年手足口病标本PCR检测阳性分别为78份、232份、129份,其中EV71分别占42.3%、48.3%、67.4%,CoxA16分别占2.6%、37.9%、10.9%,未分型的其他肠道病毒分别占55.1%、12.5%、21.7%。结论沈阳地区2009年-2011年手足口病病原体以EV71和CoxA16为主,2009年-2011优势型别均为EV71型。Objective To investigate the etiological characteristics of hand, foot and mouth disease （HFMD） from 2009 to 2011 in Shenyang and provide scientific evidence for prevention and treatment of HFMD. Methods One hundred and twenty - three fecal specimens were collected from HFMD patients in 2009, 264 fecal specimens were collected from HFMD patients in 2010 and 142 fecal specimens were collected from HFMD patients in 2011 respectively. All the specimens were tested for enterovirus by RT -PCR. Results There were 78 human enterovirus positive specimens in 2009, 232 enterovirus positive specimens in 2010 and 129 enterovirus positive specimens in 2011, in which EV71 accounted for 42.3%, 48.3%, 67.4% respectively, CoxA16 accounted for 2.6% , 37.9%, 10.9% respectively, while other untyped enterovirus accounted for 55.1% , 12.5% , 21.7% respectively. Conclusion EV71 and CoxA16 were dominant pathogens of HFMD in Shenyang from 2009 to 2011.

关 键 词：手足口病 肠道病毒 病原学检测 

分 类 号：R512.5[医药卫生—内科学]