体外受精-胚胎移植前切除积水输卵管的意义  

The significance of removing hydrosalpinx by salpingectomy before in vitro fertilization and embryo transfer

作　　者：刘见桥[1] 龙晓林[1] 陈元本[1] 陈欣洁[1] 黄艳仪[1] 孙筱放[1] 张伟良[1] 姚瑞芬[1] 

机构地区：[1]广州医学院附属广州市第二人民医院广州市妇产科研究所,510150

出　　处：《中国实用妇科与产科杂志》2001年第1期37-38,共2页Chinese Journal of Practical Gynecology and Obstetrics

摘　　要：目的　探讨体外受精 -胚胎移植 (invitrofertilization -embryotransfer ,IVF -ET)前切除积水的输卵管的意义。方法　回顾性分析因输卵管积水导致不孕而要求接受IVF -ET的 32例患者 ,其中 17例病人在IVF -ET前切除了积水的输卵管 ,共接受IVF -ET 2 7个周期 ,为观察组 ;有 15例病人未切除积水输卵管 ,共接受IVF -ET 2 6个周期 ,为对照组。比较两组病人卵巢对超排卵的反应、受精率、卵裂率、累计胚胎评分 (cumula tiveembryoscore,CES)、胚胎种植率、临床妊娠率。结果　观察组受精率、卵裂率、胚胎种植率、临床妊娠率分别为 76 9%、75 0 %、11 6 %、33 9% ,均显著地高于对照组的 6 9 2 %、6 6 7%、2 3 %、7 7% ,P <0 0 5 ;观察组CES为 (4 3 4± 11 2 ) ,非常显著地高于对照组 (36 6± 13 1) ,P <0 0 1;观察组和对照组的获卵数分别为 (13 1± 9 7)个和 (12 9± 8 2 )个 ,无显著差异。结论　IVF -ET前切除积水的输卵管可改善IVF -ET的结局 ,并且不影响卵巢对超排卵的反应。Objective\ To assess the value of removal of hydrosalpinx by salpingectomy before IVF-ET.Methods\ 32 patients with hydrosalpinx were divided into two groups.In study group,17 with hydrosalpinx were performed salpingectomy before IVF-ET,and they received 27 IVF-ET cycles.15 patients in control group with unremoved hydrosalpinx received 26 cycles.Ovary response to superovulation,fertilizatoin rate,cleavage rate,cumulative embryo score(CES),implantation rate and clinical pregnancy rate of the two groups were compared.Results\ Fertilization rate,cleavage rate,implantation rate and clinical pregnancy rate in study group were 76 9%,75 0%,11 6% and 33 9%,respectively.All of them were higher than those in control group(P<0 05),which were 69 2%,66 7%,2 3% and 7 7%,respectively.The CES of study group(43 4±11 2)was higher than that of control group(36 6±13 1)(P<0 01).The ovary response to superovulation of these two groups showed no significance.Conclusion\ Removal of hydrosalpinx by salpingectomy before IVF-ET can improve the result and shows no effects on the ovary response to superovulation.

关 键 词：体外受精 胚胎移植 输卵管积水 输卵管切除术 

分 类 号：R321-33[医药卫生—人体解剖和组织胚胎学] R713.51[医药卫生—基础医学]