二乙酰-肟法测定唾液尿素氮初探  

Discussion on Di-acethyl Oxime Method to Detect BUN in Saliva

作　　者：陈风莲[1] 邢忠[1] 张欣松[2] 

机构地区：[1]黑龙江省医院检验科,黑龙江哈尔滨150001 [2]黑龙江省临床检验中心,黑龙江哈尔滨150008

出　　处：《黑龙江医学》2001年第2期91-92,共2页Heilongjiang Medical Journal

摘　　要：目的方法　本文应用二乙酰 -肟法对 85例正常对照和 4 5例氮质血症患者唾液尿素氮进行研究 ,并对实验中的影响因素做了初步探讨。结果　唾液BUN浓度与血清BUN浓度呈正相关 ,且相关性良好 ,(r =0 983) ,唾液BUN :血清BUN =1 0 5。室温 (2 0℃ )条件下 ,含菌唾液中BUN在 2h内变化不显著 ,但随时间延长呈下降趋势 ;37℃条件下 ,BUN随时间变化显著 ;饭前或饭后漱口 30min内进行唾液BUN测定结果较为可靠。结论　唾液BUN可以作为肾功能的诊断指标之一 ,且唾液标本具有采集方便 ,患者无痛苦 ,避免穿刺感染等优点 ,尤其适用于小儿及采血不易患者。Objective To discuss the clinical significance of BUN detection in saliva and affective factors with di-acethyl oxime method. Methods The BUN in saliva samples of 85 cases of normal control group and 45 cases of azotemia patients were detected with di-acethyl oxime method and compared with serum BUN. Results There was a good positive correlation between saliva BUN and serum BUN. BUN in saliva at 20℃ kept unchanged but tended to decrease with time. BUN in saliva changed with time significantly at 37℃. Conclusion The BUN in saliva within gargling at AC or PC was reliable. The BUN in saliva in sample with available selection could be one of diagnostic reference data for kidney function in clinic. This sample selection could be easy, painless and without infection especially for children.

关 键 词：唾液 尿素氮 二乙酰-肟法 诊断指标 

分 类 号：R446.19[医药卫生—诊断学]