老年2型糖尿病与糖调节受损患者和正常人群口腔假丝酵母菌属感染的比较  

A comparative study of oral Candida infections in elderly with type 2 diabetes,patients with impaired glucose regulation and normal population

作　　者：刘宇 王彝[2] 邓悦 

机构地区：[1]重庆市红十字会医院(江北区人民医院)口腔科,重庆400020 [2]重庆市江北区中医院口腔科,重庆400020

出　　处：《中华医院感染学杂志》2014年第12期2992-2994,共3页Chinese Journal of Nosocomiology

基　　金：国家自然科学基金资助项目(81000458)

摘　　要：目的研究老年2型糖尿病与糖调节受损及正常人群的口腔假丝酵母菌属感染,以降低感染率。方法选择2009年1月-2013年7月150例老年2型糖尿病患者、150例糖调节受损患者及150名正常人群进行研究,检测分析3组受试者假丝酵母菌属阳性率、感染率及携带率,并对其唾液流量、pH值及空腹血糖值进行记录,采用SPSS18.0统计软件进行数据处理。结果老年2型糖尿病患者假丝酵母菌属阳性率、感染率分别为24.00%、8.66%,高于糖调节受损患者的9.33%、2.66%,也明显高于正常人群的7.33%、2.66%,3组数据比较差异有统计学意义(P<0.05);假丝酵母菌属携带率3组比较差异均无统计学意义;老年2型糖尿病和糖调节受损患者的唾液流量及pH值均明显低于正常对照组,但空腹血糖值均明显高于正常组,差异均有统计学意义(P<0.01)。结论老年2型糖尿病患者比糖调节受损及正常人群易发生口腔假丝酵母菌属感染;年龄、有无义齿、空腹血糖值是口腔假丝酵母菌属感染的危险因素。OBJECTIVE To study the oral Candida infections in the elderly with type 2 diabetes ,impaired glucose regulation population and normal population ,so as to reduce the infection rates .METHODS Totally 150 cases of the elderly patients with type 2 diabetes ,150 cases of patients with impaired glucose regulation and 150 cases of normal subjects from Jan 2009 to July 2013 in the hospital were selected for study , then the positive rates , infection rates and carrying rates of Candida for the three groups of were analyzed through detection ,and their salivary flow rates ,pH values as well as fasting blood sugar levels were recorded ;SPSS18 .0 was adopted for statistical analysis .RESULTS The positive rate and infection rate of the elderly patients with type 2 diabetes were 24 .00% and 8 .66% respectively ,higher than those of the patients with impaired glucose regulation （9 .33% , 2 .66% ） ,and significantly higher than those of the normal subjects （7 .33% ,2 .66% ） ,the difference between the three groups were significant （P〈 0 .05）;Candida carrying rates of the three groups showed no significant difference;salivary flow rates as well as pH values of the elderly patients with type 2 diabetes and patients with impaired glucose regulation were significantly lower than those of the normal control group ,but the fasting blood glucose levels were significantly higher than that of the normal group ,the difference was significant （P〈0 .01） . CONCLUSION As compared to patients with impaired glucose regulation and normal population , the elderly patients with type 2 diabetes are prone to oral Candida infections ;age ,presence of absence of dentures ,fasting blood glucose level are the risk factors for oral Candida infections .

关 键 词：2型糖尿病 糖调节受损 老年患者 假丝酵母菌属 

分 类 号：R181.32[医药卫生—流行病学]