应用骨填充网袋治疗椎体压缩性骨折的临床研究  

Bone filling mesh container for the treatment of vertebral compression fractures

作　　者：彭湘涛[1,2,3] 刘训伟[1,2] 金鹏[1,2] 谢志勇[1,2] 张绪平[1,2] 孙钢[1,2] 

机构地区：[1]第二军医大学济南临床学院 [2]济南军区总医院医学影像科,山东济南250031 [3]解放军第401医院放射科,山东青岛266071

出　　处：《医学影像学杂志》2014年第5期843-847,共5页Journal of Medical Imaging

摘　　要：目的：评估骨填充网袋（bone filling mesh container ，BFMCs）临床治疗椎体压缩性骨折的有效性和安全性。方法将2009年4月～2010年10月我院症状性椎体压缩性骨析的90例患者做为研究对象，男38例，女52例，年龄53～80岁，中位年龄67岁，61例（78％）为单纯性压缩骨折，23例（17％）为转移瘤，6例（5％）为血管瘤。所有患者为单节段椎体压缩性骨折并进行过保守治疗。记录术前及术后3天、1月、3月、6月疼痛评分（VAS法），并对伤椎高度及Cobb’ s角进行测量。对比术前术后疼痛评分的差异，评估伤椎高度及Cobb’s角的变化。对结果进行统计分析。结果 A、B两组均无骨水泥外渗漏，C组骨水泥椎体外渗漏5例，未出现临床症状。A、B、C各组组内术后3天、1m、3m、6m的VAS评分与术前两两比较差异有统计学意义（P﹤0．05），术后两两比较差异无统计学意义（P﹥0．05），组间术前与术后两两比较差异无统计学意义（P﹥0．05）。A、B术后椎体中部及前缘椎体抬升百分比组内比较差异均有统计学意义（P值﹤0．05），组间比较差异无统计学意义（P值均﹥0．05），C组组内比较差异无统计学意义（P值﹥0．05），C组与A、B组组间比较差异有统计学意义（P﹤0．05）。A、B组Cobb’s角变化组内术后与术前两两比较差异有统计学意义（ P﹤0.05），术后两两比较差异无统计学意义（ P﹥0．05），组间术前与术后两两比较差异无统计学意义（ P﹥0．05）。C组组内术后与术前两两比较差异无统计学意义（P﹥0．05），术后两两比较差异无统计学意义（P﹥0．05），C组与A、B组组间比较差异有统计学意义（ P﹤0．05）。结论骨填充网袋治疗症状性椎体压缩性骨折患者在改善疼痛，抬升伤椎高度，后凸畸形矫正等方面具有满意效果，骨水泥椎体外渗漏率降低，为椎体压缩性骨折提供Objective To assess the effectiveness and security of BFMCs for the treatment of vertebral compression frac-tures .Methods There were 90 cases of painful vertebral body compression fractures （from April 2009 to October 2010 ） . The indications included painful osteopomtic venebral body compression fracture ,spinal metastases and vertebral angioma . All of the cases were single segmental vertebral compression fractures and had the Experience the conservative treatment . Patients were evaluated with Visual Analogue Scale （VAS） .The anterior height ,midline height and Cobb＇s Angle of the vertebrae body were measured preoperation and postoperation （3 days ,1 month ,3 months ,6 months） .All data was send to statistical analysis .Results 1 case bone cement leakage happened in A group and B group ,5 cases happened in group C without clinical symptoms .There was a significant difference in 3 d ,1 m ,3 m and 6 m postoperation of all groups （ P〈0 .05） on VAS score compared with preoperation ,but it was not for postoperation with paired comparison （ P 〉0 .05） . There was no significant difference in paired comparison （ P〉0 .05） .There was a significant difference between the uplift of anterior and middle of Vertebral bodies postoperation of Groups A and B （ P﹤0 .05） ,the difference in the group C had no statistical significance （ P﹥0 .05） while a significant difference by comparing the group C with groups A and B （ P﹤0 .05） .There was a significant difference in the paired comparison pre-and post-operation between the Cobb’s variation of Groups A and B （ P﹤0 .05） .The difference was no significant in paried comparation postoperation （ P﹥0 .05） .There was no significant difference between postoperation and preoperation （ P﹥0 .05） .There was no significant difference in postoperative and preoperative group for C （ P﹥0 .05） while the difference was no significant in postoperative group through pairwise comparison （ P 〈0 .05） .There was a signific

关 键 词：组织工程骨材料 椎体成形术 介入放射学 椎体压缩性骨折 

分 类 号：R815[医药卫生—放射医学] R681.5[医药卫生—临床医学]