超分子化合物的荧光增敏效应及浊点萃取-荧光光谱法测定氟比洛芬  

Determination of Trace Flurbiprofen by Fluorescence Enhancement of Supermolecule and Cloud Point Extraction

作　　者：昌征[1] 昌震[2] 高乐乐[1] 

机构地区：[1]西安理工大学理学院应用化学系,陕西西安710054 [2]西安市红十字会医院,陕西西安710054

出　　处：《分析科学学报》2014年第3期405-408,共4页Journal of Analytical Science

基　　金：西安理工大学博士启动基金(No.108-211103)

摘　　要：比较氟比洛芬在乙醇介质，及对其浊点萃取后在非离子型表面活性剂Tergitol 15-S-7胶柬-乙醇介质中的荧光光谱，发现氟比洛芬的荧光发射峰有明显红移的现象，且荧光信号显著增强。研究证实Tergitol 15-S-7与氟比洛芬激发态分子之间的超分子作用力是荧光增强的主要原因。据此，提出了一种浊点萃取一荧光光谱法测定氟比洛芬的新方法。在优化的实验条件下，氟比洛芬测定的线性范围为1．0×10-8^1．0×10-6^mol·L-1^，检出限为1．1×10-9^mol·L-1^。The fluorescence emission peak of flurbiprofen shows an obvious red shift and the fluorescence intensity of flurbiprofen was significantly increased in the presence of Tergitol 15-S-7. The experimental results showed that the supramolecular interactions between Tergitol 15-S-7 and the flurbiprofen excimers played a key role for improving the flurbiprofen fluorescence properties. Based on these facts, a simple fluorometric method combined with cloud point extraction（CPE） for the preconcentration and determination of trace flurbiprofen was developed. Under optimized experimental conditions, the linear concentration range for flurbiprofen was 1.0 × 10-8^ mol.L-1^-1.0X10-6 mol.L-1^ and the detection limit was 1.1X10-9 mol·L-1.

关 键 词：超分子效应 Tergitol 15-S-7 浊点萃取 氟比洛芬 尿样 

分 类 号：O657.39[理学—分析化学]