红细胞天然免疫黏附功能在儿童手足口病中的应用  

Application of the Innate Immune Adhesion Function of Erythrocyte in Children Hand- foot-mouth Disease

作　　者：张丽霞[1] 赵瑞芹[2] 付海燕[2] 刘斌[1] 张素领[1] 王盛华[1] 刘新光[1] 

机构地区：[1]河北省儿童医院检验科 [2]河北省儿童医院感染消化科

出　　处：《现代预防医学》2014年第12期2227-2228,2248,共3页Modern Preventive Medicine

基　　金：河北省医学科学研究重点课题计划(20110017)

摘　　要：目的研究手足口病患儿红细胞天然免疫黏附功能(EIIAF)的变化及其临床意义。方法收集手足口病患儿111例,其中死亡组6例,危重组57例,对照组(普通患儿组)48例,对EIIAF进行测定。结果死亡组、危重组和对照组EIIAF检测的中位数(四分位数间距)分别为19.5(11)%、26.0(11)%和38.0(24)%。3组EIIAF分析差异有统计学意义(χ2=24.452,P<0.001),死亡组、危重组EIIAF较对照组降低,差异有统计学意义,P<0.017。结论 EIIAF对手足口病的预后判断具有参考价值。Objective This study was to investigate the change of erythrocytic innate immune adhesion function （EIIAF） in children with hand-foot-mouth disease （HFMD） and its clinical significance. Methods 111 cases were collected and divided into a death group （6 cases）, a critical group （57cases） and a control group （48 cases）. EIIAF were measured in all three groups. Results The median EIIAF （interquartite） of the death group, critical group and control group were 19.5% （11）, 26.0% （11） and 38.0% （24）, respec- tively. The difference was statistically significant （Х^2=24.452, P〈0.001）. EIIAF of the death group and critical group were significantly decreased compared to the control group （P〈0.017）. Conclusion EIIAF have important clinical significance for the diagnosis of HFMD.

关 键 词：手足口病 儿童 红细胞天然免疫黏附功能(EIIAF) 

分 类 号：R175[医药卫生—妇幼卫生保健] R392.3[医药卫生—公共卫生与预防医学]