阳离子交换树脂对新奥霉素的吸附性能分析与研究  

ADSORPTION PROPERTIES OF XINAOMYCIN ON ION EXCHANGE RESINS

作　　者：宋玉龙[1,2] 周金燕[1] 杨杰 谭红[1] 

机构地区：[1]中国科学院成都生物研究所环境与应用微生物重点实验室,成都610041 [2]中国科学院大学,北京100039 [3]四川省环境微生物重点实验室,成都610041

出　　处：《离子交换与吸附》2014年第2期97-107,共11页Ion Exchange and Adsorption

基　　金：国家科技支撑计划项目(2011BAE06B04-03)

摘　　要：采用阳离子交换树脂分离提取核苷肽类农用抗生素新奥霉素。实验结果表明,在8种阳离子交换树脂中,7320树脂吸附效果最好,在pH=7时,树脂的交换容量最大;3%氨水可高效地将新奥霉素从7320树脂上解析下来,解析率为95.00%。静态吸附动力学符合Lagergren准二级速率方程,颗粒内扩散为影响吸附速率的主要控速步骤,吸附速率常数为k=0.00738g/(mg·min)。吸附等温线符合Langmuir方程,由热力学平衡方程计算得ΔH=60.93kJ/mol,ΔS>0,ΔG<0,表明该交换过程是自发的、吸热、熵增加的过程。在动态实验中,发酵液以1BV/h上样、3%氨水以2BV/h进行解吸,解吸液经减压浓缩得到褐色膏状物质,新奥霉素得率为79.96%。Xinaomycin is one of the agricultural peptidyl nucleoside antibiotics. The adsorption properties of Xinaomycin on resins were investigated. The 7320 resin has the highest adsorption efficiency among eight types of ion exchange resins. The adsorption efficiency of 7320 resins for Xinaomycin was 93.60% under pH 7.0 and the desorption efficiency eluted by 3% ammonia could reach 95.00%. Kinetic experiments showed that the Pseudo-second-order rate model could satisfactorily describe the experimental data with the adsorption rate constant of 0.00738g/（mg.min）. The adsorption of Xinaomycin on 7320 resins obeyed Langmuir isotherm, and the value of the thermodynamic equilibrium functions （AG〈0, AH〉0, AS〉0） were determined, so the adsorption of Xinaomycin on 7320 resins was a spontaneous, endothermic and entropy increasing process. The dynamic experimental results indicated that the optimal feeding rate and desorbing rate were IBV/h and 2BV/h, respectively. The elution was concentrated to obtain the brown paste. Through this process, the average recovery efficiency of Xinaomycin was 79.96%.

关 键 词：新奥霉素 离子交换树脂 吸附 解吸 

分 类 号：O647-3[理学—物理化学]