清远地区男性不育症患者精液质量与年龄的关系  

The relationship between the semen quality and age in infertile men in Qingyuan

作　　者：颜秋霞 冼英杰[1,2] 周秀琴 陈润强[1,2] 邱佩嫦 王秋香[1,2] 李艳红 何榕葵[1,2] 陈彩蓉 

机构地区：[1]广东省清远市人民医院 [2]暨南大学医学院附属清远医院生殖中心,广东清远511518

出　　处：《国际检验医学杂志》2014年第11期1390-1391,1394,共3页International Journal of Laboratory Medicine

基　　金：国家自然科学基金资助项目(81170613;81270740;81101922);广东省清远市科技计划项目(2012B011204127);深圳市基础研究计划杰出青年项目(JC201005260216A)

摘　　要：目的：探讨清远地区男性不育症患者精液质量与年龄的关系。方法选取该院生殖中心男科门诊就诊的727例男性不育症患者为研究对象，依据年龄分为5组：≤25岁、＞25～30岁、＞30～35岁、＞35～40岁、＞40岁。采用计算机辅助精液分析（CASA）技术以及 Diff-Quick 快速染色法进行精液质量分析。结果＞30～40岁年龄段男性精液浓度较高，各年龄组间精液浓度变化没有统计学差异（P ＞0．05）。随着年龄的增长，前向运动（PR）精子比例、精子总活力以及精子存活率呈相对下降趋势，但各组间无明显统计学差异（P ＞0．05）。＞25～30岁组各项精液参数指标均达到 WHO 标准的比例最高，占该组人数的38．19％，＞40岁组比例最低，占该组人数的27．42％。结论随着年龄的增长，男性的精液质量呈下降趋势，但是不育症可发生在生育期男性的任何阶段。Objective To study the relationship between the semen quality and age in infertile men in Qingyuan.Methods 727 cases of infertile men from Reproductive Medicine Center outpatient were enrolled and divided into 5 groups：≤ 25,〉 25 - 30,〉30-35,〉35-40,〉40 age groups.The semen characteristics were carried out by calculator assistance sperm analysis（CASA） technique and Diff-Quick staining method.Results The sperm density of 〉30 -35 age group was the highest,but there was no significantly difference from other groups（P 〉0.05）.Semen analysis showed that the rates of PR,PR＋NP and survival sperm were on downward trends with the increase of age,but not statistically significant（P 〉0.05）.38.19% of 〉25 -30 age group reached WHO′s semen parameters standard,which was the highest proportion among 5 groups.And the proportion in 〉40 age group was the lowest,which counted for 27.42%.Conclusion The semen quality shows a down trend with the increase of age,however,the infertility could occur in the reproductive men at any stage.

关 键 词：男性不育症 精液质量 年龄 

分 类 号：R698.2[医药卫生—泌尿科学]