绝经女性冠心病患者雄激素水平的检测及临床意义  

The detection of androgen and its clinical significance for postmenopausal women with coronal atherosclerosis heart disease

作　　者：桂瑞丰 李超伟[1] 

机构地区：[1]湖北省黄冈市中心医院检验科,湖北黄冈438000

出　　处：《国际检验医学杂志》2014年第11期1437-1438,共2页International Journal of Laboratory Medicine

摘　　要：目的探讨绝经女性冠心病患者雄激素的变化及其检测的临床意义。方法根据冠状动脉造影结果将218例疑似冠心病的绝经妇女分为观察组(冠心病患者93例)、对照组(非冠心病患者125例),检测2组妇女的患者血压、血糖、血脂[包括总胆固醇(TC)、三酰甘油(TG)、低密度脂蛋白胆固醇(LDL-C)、高密度脂蛋白胆固醇(HDL-C)]、激素(雄激素睾酮、雄烯二酮)指标。结果观察组除血糖与对照组比较差异无统计学意义(P>0.05)外,其余指标(收缩压、舒张压、TC、TG、LDL-C、HDL-C、雄激素睾酮、雄烯二酮)均有显著变化,且差异有统计学意义(P<0.05)。结论绝经女性冠心病患者较非冠心病绝经女性雄激素水平升高,检测雄激素水平对辅助该病的病情监测及诊断具有临床意义。Objective To discuss the change of androgen level in postmenopausal women with coronal atherosclerosis heart disease, and to discuss its clinical significance. Methods According to the results of coronary angiography, 218 cases of possible coronal atherosclerosis heart disease patients were divided into the observational group with 93 cases of coronal atherosclerosis heart disease patients, and the control group with non-coronal atherosclerosis heart disease patients. The levels of TC,TG, LDL-C, HDL- C,testostemne and andmstenedione in blood were investigated in two groups. Results The level of blood glucose was not statistically different between the two groups（P〉0.05）, however, the levels of systolic and diastolic blood pressure, TC, TG, LDL-C and HDL-C were statistically different between the two groups （P 〈0. 05）. Conclusion The level of androgen in postmenopausal women with coronal atherosclerosis heart disease are higher than postmenopausal women without coronal atherosclerosis heart disease. Androgen detection is useful for the monitoring and diagnosis for postmenopausal women with coronal atherosclerosis heart disease.

关 键 词：雄激素 绝经 女性 冠心病 

分 类 号：R541.4[医药卫生—心血管疾病]