蚊虫嗅觉受体的研究进展  

ADVANCES IN RESEARCH OF ODORANT RECEPTOR PROTEINS OF MOSQUITOES

作　　者：代玉华[1,2] 赵忠懿 程鹏[1] 刘丽娟[1] 公茂庆[1] 

机构地区：[1] 山东省医学科学院,山东省寄生虫病防治研究所,山东济宁272033 [2] 河南出入境检验检疫局,郑州450003

出　　处：《寄生虫与医学昆虫学报》2014年第1期59-64,共6页Acta Parasitologica et Medica Entomologica Sinica

基　　金：国家自然科学基金项目（No.81201317）;山东省优秀中青年科学家科研奖励基金（No.bs2011SW032）

摘　　要：蚊虫是传播疟疾、登革热、黄热病、日本脑炎等疾病的重要媒介，嗅觉系统影响着蚊虫的栖息地选择、繁殖、觅食、吸血、趋避及信息传递等行为。嗅觉受体是嗅觉系统的关键成分之一，近年来相关的研究较多。本文简介了蚊虫嗅觉受体蛋白的特征、表达与功能，此外，综述了结构和功能高度保守的Or83 b受体蛋白以及蚊虫驱避剂的研究进展。Mosquitoes are one of the most important vectors for transmitting diseases such as malaria , dengue fever and yellow fever.In mosquitoes, the olfactory system plays a crucial role in many types of behavior, including nectar feeding, host preference selection and oviposition.Odorant receptors （ ORs ） are comprised of highly variable odorant-binding subunits associated with one conserved co-receptor.They are potential molecular targets for the development of novel mosquito attractants and repellents.ORs have been identified in the malaria mosquito, Anopheles gambiae, and in the yellow fever mosquito, Aedes aegypti.This review enclosed the lately research progress of ORs, including the characteristics of structure, expression regulation and physiological function.Moreover, a highly conserved, broadly expressed olfactory receptor Or83b were summarized in the article.The relationship between OR with the development of mosquito repellents was also involved in the present paper.

关 键 词：蚊虫 嗅觉受体 表达 功能 驱避剂 

分 类 号：S476.13[农业科学—农业昆虫与害虫防治]