急救重度有机磷中毒伴呼吸衰竭的急救对策及预后分析  

Analysis of the Emergency Measures for Severe Organophosphate Poisoning with Respiratory Failure and the Prognosis

作　　者：林健球[1] 郑永汉[1] 

机构地区：[1]广东医学院附属三水医院急诊科,广东佛山528100

出　　处：《中外医疗》2014年第11期16-17,共2页China & Foreign Medical Treatment

摘　　要：目的分析研究重度有机磷中毒伴呼吸衰竭患者的急救方法 ,分析解磷定对患者的治疗价值。方法选择2010年7月—2013年6月该院重度有机磷中毒伴呼吸衰竭的患者58例为研究对象,随机分为两组。对照组使用一般治疗方法,实验组使用解磷定治疗,对比观察两组治疗后的效果。结果实验组患者带机时间短,气管切开率低,患者3 d内脱机率高,两组对比差异有统计学意义(P<0.05);实验组病死率低于对照组患者(P<0.05)。结论对重症有机磷中毒伴呼吸衰竭患者给予解磷定急救治疗可以提高救治效果,患者撤机快,呼吸衰竭时间缩短,值得应用。Objective To analyze the first-aid method for patients with severe organophosphate poisoning and respiratory failure, and the ther-apeutic value of pralidoxime for the patients. Methods 58 cases of patients with severe organophosphate poisoning and respiratory failure admitted in our hospital from July, 2010 to June, 2013 were selected as the subjects, and they were randomly divided into two groups. The control group was treated with the general treatment method, and the experimental group was treated with prali-doxime. The treatment effect of two groups was observed and compared. Results The patients in the experimental group had short-er time with a ventilator, lower rate of tracheotomy, higher withdrawal probability of ventilator within 3d, the differences between two groups were statistically significant （P〈0.05）; the mortality of the experimental group was lower than that of the control group （P〈0.05）. Conclusion Pralidoxime given to the patients with severe organophosphate poisoning and respiratory failure for first-aid treatment can improve the treatment effect; patients need shorter time of needing for ventilation with shorter respiratory failure time, which is worthy of application.

关 键 词：有机磷中毒 呼吸衰竭 急救 解磷定 

分 类 号：R59[医药卫生—内科学]