原发疾病对新生儿红细胞输注效果影响  

Effect of the primary diseases on transfusion about the newborn red blood cells

作　　者：曾德理[1] 张清[1] 覃碧静 袁茜茜[1] 

机构地区：[1]广西壮族自治区妇幼保健院输血科,南宁530003

出　　处：《现代仪器与医疗》2014年第2期79-82,共4页Modern Instruments & Medical Treatment

摘　　要：目的探讨疾病对新生儿红细胞输注效果的影响,以确定输血疗效,为临床提供安全有效的输血.方法：选择日龄在0 ～ 30d 输注红细胞悬液（不包括换血及失血性病例）的患儿共150 例,按疾病诊断分为败血病组、肺炎组、ABO 溶血病组及单纯新生儿贫血病组,比较各组输注红细胞悬液后24h 内Hb 的变化,Hb 值不升或下降的为红细胞输注无效.结果：败血病组、ABO 溶血病组、肺炎组、单纯新生儿贫血病组Hb 升幅分别为0.24%、1.51%、12.75%、22.81%,无效输注率分别为54.17%、 46.43%、25%、 16.67%,各组Hb 上升幅度比较：单纯新生儿贫血病组〉 肺炎组〉 ABO 溶血病组、败血病组.红细胞输注无效率比较：单纯新生儿贫血病组﹤肺炎组﹤ ABO 溶血病组、败血病组,组间差异有统计学意义.结论：新生儿红细胞输注效果与所患疾病有关,各种疾病输血均有一定比例无效.因此新生儿输血应做到合理输血,注意疾病本身影响,及时检测Hb,及时调整治疗方案,以提高治疗效果.Objective:Investigating the infl uence of diseases on transfusion about the Newborns Red blood cells to ensure blood transfusion curative effect and provide a safe and effective clinical bolld transfusion. Methods: Select red cell suspension liquid of day-age in 0-30d in a total of 152cases(excluding exchange transfusion cases and cases with hemorrhagic). Cases according to diseases are divided into sepsis group,pneumonia group, ABO hemolytic disease group and Pure neonatal anemia group. Compare the changements of Hb values according to different group with in 24h after transfusion of red cell suspension liquid. Hb values do not rise or fall,that is, the transfusion is invalid. Result:For sepsis group,ABO hemolytic disease, pneumonia group and pure neonatal anemia group it accounted for 0.24 per cent 1.51 per cent 12.75 per cent and 22.81 per cent of the rate of rise respectively. Rates of Transfusion invalid of those groups are 54.17 per cent,46.43 per cent,25 per cent, 16.67 per cent respectively. Compare with data of those groups, the rate of rise about Hb valuse: pure neonatal anemia group<pneumonia group<ABO hemolytic disease and sepsis group,P<0.05.The rate of transfusion invalid : pure neonatal anemia group<pneumonia group<ABO hemolytic disease and sepsis group,P<0.05. Conclusion: The effects of newborns' red cell transfusion is related to diseases. Cases suffering from any disease can have chance for invalid transfusion. Therefore blood transfusion for newborns should be reasonable transfusion,and should pay attention to disease treatment and have a timely detection of Hb values,so that can timely adjust the treatment plan and improve treatment effect.

关 键 词：新生儿 红细胞 血红蛋白 疾病 

分 类 号：R457[医药卫生—治疗学]