80岁以上患者冠状动脉旁路移植术后近期疗效和围术期处理  

Perioperative management and short-term outcomes for patients aged〉80 years undergoing coronary artery bypass grafting

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作  者:刘健[1] 施盛[1] 王利民[1] 袁忠祥[1] 

机构地区:[1]上海交通大学附属第一人民医院心血管外科,200080

出  处:《中华老年医学杂志》2014年第6期585-587,共3页Chinese Journal of Geriatrics

摘  要:目的分析80岁以上患者冠状动脉旁路移植术(CABG)的近期疗效和围术期处理。方法2002年1月至2012年12月118例80岁以上行CABG的患者(81~89岁组),取同期1034例60-80岁患者为对照组,利用多因素回归分析统计〉80岁组患者术后死亡和各种并发症的风险。结果81~89岁组术后死亡8例(6.8%),对照组病死率3.1%(32例)。多因素分析结果显示,与对照组比较,81~89岁组患者术后病死率是对照组的3.45倍(OR=3.45,95%CI:2.86~4.23),术后需做透析的风险上升2.56倍(OR=3.56,95%CI:3.01~4.32),术后再次插管的风险上升2.87倍(OR=3.87,95%CI:3.45~4.87),切口延期愈合的风险也上升3.05倍(OR=4.05,95%CI:3.47~5.74),机械通气时间延长的风险上升2.76倍(OR=3.76,95%CI:3.43~5.01),监护时间延长的风险上升1.98倍(OR=2.98,95oACI:2.67~4.12),住院时间延长的风险也上升1.87倍(OR=2.87,95%CI:2.36~3.96)。结论80岁以上患者CABG后死亡和并发症发生风险增加,需加强围术期管理。Objective To review the experience of perioperative management and effect of coronary artery bypass grafting (CABG) for patients of aged〉80 years. Methods We studied 118 cases with CABG- for patients of age〉80 years from January 2002 to December 2012. The other 1034 cases with CABG for patients aged 60-80 years were enrolled as control group. Logistic regression analysis was used to assess the effect of age on operative mortality and morbidity. Results The recent mortality was higher in group aged〉80 years [6.8%(8 cases) vs. 3.1%(32 cases)]. Through multivariate logistic regression, the patients aged〉80 years versus control were concerned about some postoperative adverse events as follows: higher mortality( OR: 3.45,95% CI: 2.86-4.23), dialysis (OR:3.56,95%CI:3.01-4.32) and re-intubation(OR: 3.87,95%CI:3.45-4.87), delayed healing of incision( OR: 4.05,95 % CI: 3.47-5.74), prolonged mechanical ventilation( OR: 3.76,95% CI: 3.43- 5.01), prolonged ICU stay (OR= 2.98,95% CI: 2.67-4.12), prolonged hospital stay(OR:2.87, 95%CI: 2.36-3.96) . Conclusions Age〉80 years is an important factor of postoperative mortality and morbidity for CABG. We need pay more attention to perioperative management.

关 键 词:冠状动脉旁路移植术 非体外循环 围术期 治疗结果 

分 类 号:R654.2[医药卫生—外科学]

 

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