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作 者:王海[1] 严铸云[1] 沈昱翔[1] 何冬梅[1] 兰英[1] 万德光[1]
机构地区:[1]成都中医药大学药学院中药材标准化教育部重点实验室,四川成都611137
出 处:《中药新药与临床药理》2014年第3期333-338,共6页Traditional Chinese Drug Research and Clinical Pharmacology
基 金:国家自然科学基金项目(81173493);国家十一五科技支撑计划项目(2006BAI09B03-4)
摘 要:目的对不同产地丹参的表面、断面、提取液的颜色及药材有效成分之间的相关性进行分析研究。方法运用色彩色差计法和紫外一可见分光光度计进行颜色色度值(L*a*L*)测定,用高效液相色谱法测定药材有效成分的含量,采用STATA软件进行统计分析。结果测量亮度(L*)值的变异系数(RSD)为1.1%~1.9%,表明方法稳定可行。L*值与药材的红色程度存在显著的线性关系,且各组RSD值均小于3%,线性拟合程度较好。结论丹参药材表面颜色的色度值与丹参酮类成分具有正相关性,而断面的颜色变化与丹参有效成分的含量无相关性。Objective To analyze the correlation of effective constituents with the color of medicinal material surface, cross section, extraction solution of Radix Salviae Mihiorrhizae from different habitats. Methods The colorimeter, spectrophotometer, HPLC, STATA software were used in this study. Results The results showed the RSD (%) of chromatic value (L*) was 1.1 %-1.9 %, significantly having a linearity with the red depth of Radix Salviae Mihiorrhizae. And R value of each group was no more than 3 % with good linear degree, indicating that those research methods were feasible and had better line fitting. Conclusion This study reveals the color depth of radix surface is positively correlated with tanshinone compounds , but has no correlation with the effective constituents of Radix Salviae Mihiorrhizae.
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