Fcγ受体在胎盘细胞的分布  

Distribution of Fc γ receptor in human placenta

作　　者：刘蓬勃[1] 徐德忠[2] 王歆[2] 李玉松[3] 王文勇[3] 

机构地区：[1]第四军医大学预防医学系流行病学教研室陕西西安710033 [2]第四军医大学预防医学系流行病学教研室 [3]第四军医大学基础部病理学教研室

出　　处：《第四军医大学学报》2001年第5期459-461,共3页Journal of the Fourth Military Medical University

基　　金：国家自然科学基金资助项目! (3 980 0 15 2 )

摘　　要：目的　检测 Fcγ受体 (Fcγ R)在胎盘组织的分布 .方法　免疫荧光染色法结合普通荧光显微镜观察 .结果　人胎盘滋养层细胞表面存在 Fcγ R ,主要分布于滋养层细胞和绒毛间质细胞 .Fcγ R 主要存在于绒毛间质细胞 .Fcγ R 在胎盘的各层细胞均未检测到 .另外 ,这 3型 Fcγ R在绒毛间隙的母血细胞中也存在 .结论　 Fcγ R 分布在不同的胎盘细胞 ,提示可能与其不同功能有关 .AIM To detect the distribution of Fc γ R in human placenta. METHODS Immunofluorescent technology and fluorescence microscopy were used. RESULTS HBsAg seropositive and seronegative placenta tissues were tested for Fc γ R by immunofluorescent technology. We found that Fc γ RⅢ was mainly expressed on trophoblast cells (TC) and villous meseachymed cells (VMC), Fc γ RⅡ only on VMCs and Fc γ RⅠ was not found on any placenta cells. In addition, all three types of Fc γ R existed in inter villous space of mother bloodstream. CONCLUSION Three types of Fc γ R were found in different placenta cells, which suggests they may be in correlation with their functions.

关 键 词：FCΓ受体 免疫荧光染色 胎盘细胞 分布 

分 类 号：R714.56[医药卫生—妇产科学]