浅低温对大鼠血浆中精氨酸加压素、血管紧张素Ⅱ含量的影响  

Effects of plasma AVP and AngⅡ in the process of cold stimulation

作　　者：薛秀兰[1] 曹惠君[1] 

机构地区：[1]佳木斯大学基础医学院病生教研室,佳木斯154003

出　　处：《黑龙江医药科学》2001年第1期5-6,共2页Heilongjiang Medicine and Pharmacy

摘　　要：目的：探索不同低温条件下大鼠血浆AVP、AngⅡ含量的变化机制，为内分泌及低温领域提供一定的理论基础。方法：本实验采用低温模型，使用放射免疫法观察以上指标。结果：与对照组相比，实验各组AVP、AngⅡ差异具有显著性(P<0.01)。其中8℃~10℃组和-1℃^-2℃组显著升高。2℃~4℃组显著下降。结论：浅低温可明显影响AVP、AngⅡ含量的变化，AVP、AngⅡ参与体温调节。Objective: To study the changes in plasma AVP and AngⅡ and the change mechanism in different hypothermia in rats for providing a theoretical basis for neuroendocrinology and hypothermia field. Method: The effects of cold stimulation on the plasma AVP and AngⅡ were observed by RIA. Results: Compared to the control group, the plasma AVP and AngⅡ in the experimental groups were increased significantly (P<0.01). Conclusion: It is suggested that the cold stimulation has obvious effects on plasma AVP and AngⅡ and AVP and AngⅡ is involved in body temperature regulation.

关 键 词：浅低温 精氨酸加压素 血管紧张素Ⅱ 血浆 

分 类 号：R446.112[医药卫生—诊断学]