不同方法治疗幼年型类风湿性关节炎临床效果  

Methods the clinical effect of treatment of juvenile rheumatoidarthritis

作　　者：周文元[1] 

机构地区：[1]桃源县人民医院儿科,湖南常德415700

出　　处：《中国卫生产业》2014年第15期13-14,16,共3页China Health Industry

摘　　要：目的探讨不同方法治疗幼年型类风湿性关节炎(JRA)临床治疗效果。方法对在我院自2009年12月—2013年1月接收治疗的64例幼年型类风湿性关节炎患儿入院资料进行分析,根据患儿入院时间(单、双日)分为两组。对照组患儿采用阿斯匹林配强的松治疗,实验组采用布洛芬配合甲氨蝶呤(MTX)治疗,比较两组患儿临床治疗效果。结果实验中医护人员对患者进行35 d治疗,实验组患者治疗总有效率为93.75%,明显优于对照组患者(总有效率为85%);实验中,实验组患者有3例患者治疗后复发,复发率达到9.37%,明显高于对照组患者。结论 MTX与布洛芬合用作为JRA的一线药物,治疗效果较好,能够有效的改善患儿临床症状,减轻患儿痛苦,值得推广应用。Objective To investigate the different methods in the treatment of juvenile rheumatoid arthritis （JRA） clinicalcurative effect.Methods In my hospital from 2009 December to 2013 January treatmentreceived 64 cases of juvenile rheumatoid arthritis in children admitted to hospital were analyzed, according to the children in the hospital （single,double time） divided into two groups. Patients in the control group withprednisone in the treatment with aspirin, ibuprofen was used in the experimental group with methotrexate （MTX） treatment, compared two groups of clinical curative effect.Results The medical staff in 35 days of treat-ment on patients, patients in the experimental group the total effective rate was 93.75%, significantly better than the control group （the total effective rate was 85%）; the experiment, the experimental group patients had recurrence in 3 patients after the treatment, the recurrence rate of 9.37%, significantly higher than the control grouppatients.Conclusion MTX in combination with ibuprofen as first-line JRA treatment,good effect, can effectively improve the clinical symptoms, reduce the pain of patients, it is worthy of popularization and application.

关 键 词：幼年型类风湿性关节炎 阿斯匹林配强的松 布洛芬配合甲氨蝶呤 治疗效果 

分 类 号：R725.9[医药卫生—儿科]