急性冠脉综合征患者D-二聚体检测的临床意义  

The clinical significance of measuring plasma D-dimer level in patients with acute coronary syndrome

作　　者：谢怡怡[1] 

机构地区：[1]浙江大学医学院附属第二医院检验科,浙江杭州310009

出　　处：《实验与检验医学》2014年第3期285-286,共2页Experimental and Laboratory Medicine

摘　　要：目的探讨血浆D-二聚体水平在急性冠脉综合征(ACS)患者中的变化与临床意义。方法检测121例急性冠脉综合征(ACS)患者血浆D-二聚体水平,其中不稳定心绞痛(UAP)患者43例,非ST段抬高型心肌梗死(NSTEMI)患者30例,ST段抬高型心肌梗死(STEMI)患者48例,与50例对照组比较,并进行统计分析。结果 ACS各组血浆D-二聚体水平均高于对照组(P<0.05);STEMI组血浆D-二聚体水平高于NSTEMI组(P<0.05)和UAP组(P<0.05)。结论 ACS患者血浆D-二聚体水平增高对ACS的防治和病情的观察有重要的临床意义。Objective To evaluate the changes of plasma D-dimer level in the patients with acute coronary syndrome （ACS） and its clinical significance. Methods Plasma D-dimer levels of 121 patients with acute coronary syndrome （ACS） were detected, among them, 43 patients with unstable angina pectoris （UAP）, 30 patients with non ST-elevation myocardial infarction （NSTEMI）, and 48 patients with ST-elevation myocardial infarction（STEMI）. Their plasma D-dimer levels were compared with those of 50 cas-es in control group by statistical analysis. Results The plasma D-dimer level in each ACS group was higher than that in control group （P〈0.05）. The plasma D-dimer level in STEMI group was higher than those in NSTEMI group（P〈0.05） and UAP group（P〈0.05）. Conclusion The increase of plasma D-dimer in patients with ASC has an important clinical significance for the prevention of ACS and condition monitoring.

关 键 词：急性冠脉综合征 D-二聚体 心肌梗死 

分 类 号：R446.111[医药卫生—诊断学] R543.3[医药卫生—临床医学]