东北地区208例肾病现役军人肾活检病理与临床资料分析  

Renal biopsy and clinical data of 208 soldiers in active service with nephropathy in Northeast China

作　　者：张德伟[1] 洪敏[1] 关欣[1] 王沙西[1] 梅煜明[1] 郑红光[1] 

机构地区：[1]沈阳军区总医院肾内科,辽宁沈阳110016

出　　处：《解放军医学院学报》2014年第7期677-679,共3页Academic Journal of Chinese PLA Medical School

基　　金：辽宁省科技攻关课题(20102250036)~~

摘　　要：目的分析东北地区现役军人肾病病理构成及临床特点,为东北地区部队防治肾病提供依据。方法对我院2003年6月-2011年12月行肾活检的208例现役军人资料进行回顾性分析。结果原发性肾小球疾病占比最高,共184例(88.5%),其中男性175例(91.2%),女性9例(64.3%)。原发性肾小球疾病以系膜增生性肾小球病变为主,共160例(76.9%),其中IgA肾病93例(44.7%)。无症状的尿检异常达46例(22.1%),其中IgA肾病32例(69.6%)。东北籍军人及来自其他地区军人肾病病理构成无统计学差异(P>0.05),但东北籍军人毛细血管内增生性肾炎发病率高于其他地区,而膜性肾病发病率低于其他地区。军官中IgA肾病比例高于士兵(P<0.05),士兵IgM肾病及单纯系膜增生性肾炎发病率高于军官,但无统计学差异(P>0.05)。结论东北地区现役军人肾病以原发性肾小球疾病为主,IgA肾病发病率最高,无症状尿检异常发生率较高,不同籍贯、不同性别军人以及军官和士兵肾病病理构成有所不同,防治工作应有区别。Objective To provide the evidence for prevention and treatment of nephropathy by analyzing the pathological and clinical features of active service soldiers in Northeast China. Methods Clinical data about 208 active service soldiers who underwent renal biopsy in our hospital from June 2003 to December 2011 were retrospectively analyzed. Results Of the 208 soldiers, 184 （88.5%） including 175 （91.2%） males and 9 （64.3%） females were diagnosed with primary glomerular disease, 160 soldiers （76.9%） were diagnosed with mesenteric proliferative nephritis including 93 （44.7%） with IgA nephropathy, 46 （22.1%） with no symptoms were found to have abnormal urine test including 32 （69.6%） with IgA nephropathy. No significant difference was found in pathologic types between soldier from Northeast China and those from other areas （P 〉 0.05）. However, the incidence of endocapillary proliferative glomerulonephritis was higher while that of mesenteric proliferative nephritis was lower in soldiers from Northeast China than in those from other areas （P 〈 0.05）. No significant difference was observed in the incidence of IgM nephropathy and mesenteric proliferative nephritis although it was higher in soldiers than in officers （P 〉 0.05）. Conclusion Primary glomerular disease is dominant in active service soldiers in Northeast China. The incidence of IgA nephropathy is the highest followed by asymptomatic nephropathy with abnormal urine test. The pathologic types are different in different gender officers and soldiers from different places, thus different prevention and treatment measures should be taken for them.

关 键 词：肾活检 病理 军事人员 

分 类 号：R453.9[医药卫生—治疗学]