左卡尼汀片在4种不同介质中的溶出行为比较  

Dissolution behavior comparison of Levocarnitine Tablets in four different dissolution medias

作　　者：缪维芳[1] 李杰[1] 吴秀兰[2] 

机构地区：[1]苏州卫生职业技术学院,苏州215000 [2]江苏正大天晴药业股份有限公司,苏州215000

出　　处：《海峡药学》2014年第5期26-27,共2页Strait Pharmaceutical Journal

摘　　要：目的比较左卡尼汀片在4种不同介质中的溶出行为。方法采用桨法进行左卡尼汀片的溶出试验,采用高效液相色谱法测定药物浓度。结果左卡尼汀片在4种溶出介质中均有较好的溶出。结论左卡尼汀片对任何体质患者均有一定的疗效。OBJECTIVE To compare the dissolution behavior of Levocarnitine Tablets in four different dissolu-tion medias.METHODS The dissolution test of Levocarnitine Tablets was taken with paddle method and drug con-centrations were measured by HPLC method.RESULTS There was good dissolution of Levocarnitine Tablets in four dissolution media.CONCLUSION The tablet of Levocarnitine has some curative effect on patients in any body constitution.

关 键 词：左卡尼汀片 4种介质 溶出行为 

分 类 号：R927.2[医药卫生—药学]