Extensive diversification of IgH subclass-encoding genes and IgM subclass switching in crocodilians  

出　　处：《Science Foundation in China》2014年第1期28-28,共1页中国科学基金（英文版）

摘　　要：Immunoglobulins(Igs)are essential components of the adaptive immune system and are expressed only in jawed vertebrates,including cartilaginous fish,bony fish,amphibians,reptiles,birds and mammals.Antigen-binding regions(variable regions)and effector regions(constant regions)are pivotal to Ig functions.From an evolutionary perspective,comparative studies have provenImmunoglobulins （Igs） are essential components of the adaptive immune system and are expressed only in jawed vertebrates, including cartilaginous fish, bony fish, amphibians, reptiles, birds and mammals. Anti- gen-binding regions （variable regions） and effector re- gions （constant regions） are pivotal to Ig functions. From an evolutionary perspective,

关 键 词：编码基因 多元化 IGM 免疫球蛋白 鳄鱼 开关 重子 组成部分 

分 类 号：Q75[生物学—分子生物学]